English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Genetic diversity of HLA system in three populations from Chihuahua, Mexico: Chihuahua City, Ciudad Juárez and rural Chihuahua

Pacheco-Ubaldo, H., Adalid-Sáinz, C., Barquera, R., Clayton, S., Arrieta-Bolaños, E., Delgado-Aguirre, H., et al. (2020). Genetic diversity of HLA system in three populations from Chihuahua, Mexico: Chihuahua City, Ciudad Juárez and rural Chihuahua. Human Immunology, 81(9), 485-488. doi:10.1016/j.humimm.2019.05.014.

Item is

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Pacheco-Ubaldo, Hanna, Author
Adalid-Sáinz, Carmen, Author
Barquera, Rodrigo1, Author                 
Clayton, S.1, Author           
Arrieta-Bolaños, Esteban, Author
Delgado-Aguirre, Héctor, Author
González-Medina, Liliana, Author
Hernández-Zaragoza, Diana Iraíz, Author
Escareño-Montiel, Néstor, Author
Morán-Martínez, Javier, Author
Bravo-Acevedo, Alicia, Author
Lona-Sánchez, Abraham, Author
González-Martínez, Marisela del Rocío, Author
Jaramillo-Rodríguez, Yolanda, Author
Salgado-Adame, Antonio, Author
la Cruz, Federico Juárez-de, Author
Zúñiga, Joaquín, Author
Yunis, Edmond J., Author
Bekker-Méndez, Carolina, Author
Granados, Julio, Author
Affiliations:
1Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society, ou_2074310              

Content

show
hide
Free keywords: HLA, Immunogenetics, Population genetics, Chihuahua, Admixture
 Abstract: We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 461 Mexicans from the state of Chihuahua living in Chihuahua city (N = 119), Ciudad Juárez (N = 106) and rural communities (N = 236), to obtain information regarding allelic and haplotypic frequencies and their linkage disequilibrium. We find that the most frequent haplotypes found in the state of Chihuahua include seven Native American and three European haplotypes. Admixture estimates revealed that the main genetic components in Chihuahua are European (52.12 ± 0.88 by ML; 41.53 of European haplotypes) and Native American (39.51 ± 2.17 by ML; 37.45 of Native American haplotypes), while African genetic component was less apparent (8.36 ± 1.47 by ML; 11.70 of African haplotypes).

Details

show
hide
Language(s): eng - English
 Dates: 2019-06-042020-09
 Publication Status: Issued
 Pages: 4
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1016/j.humimm.2019.05.014
Other: shh2253
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Human Immunology
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: New York, N.Y. : Elsevier
Pages: - Volume / Issue: 81 (9) Sequence Number: - Start / End Page: 485 - 488 Identifier: ISSN: 0198-8859
CoNE: https://pure.mpg.de/cone/journals/resource/954925492912