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  Deep CEST MR Fingerprinting at 7T Reveals Tumor Apoptotic Response to Oncolytic Virotherapy In Vivo

Perlman, O., Ito, H., Herz, K., Shono, N., Nakashima, H., Zaiss, M., et al. (2020). Deep CEST MR Fingerprinting at 7T Reveals Tumor Apoptotic Response to Oncolytic Virotherapy In Vivo. Poster presented at 11th Annual Scientific Symposium on Ultrahigh Field Magnetic Resonance: Clinical Needs, Research Promises and Technical Solutions, Berlin, Germany.

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Perlman, O, Author
Ito, H, Author
Herz, K1, 2, Author              
Shono, N, Author
Nakashima, H, Author
Zaiss, M1, 2, Author              
Chiocca, EA, Author
Cohen, O, Author
Rosen, MS, Author
Farrar, CT, Author
Affiliations:
1Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

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 Abstract: Oncolytic virotherapy (OV) is a promising treatment for high mortality cancers.1Non-invasive monitoring of OV is essential for optimizing the clinical outcome and providing an improved understanding of the interactions between the virus and its tumor-host. Chemical exchange saturation transfer (CEST) MRI is a molecular imaging technique that may shed new light on OV, as it is capable of detecting pro-tein concentration and pH changes. However, clinical translation of CEST methods has been hindered by the qualitative nature of the image contrast and the long image acquisition times.

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 Dates: 2020-09
 Publication Status: Published online
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Title: 11th Annual Scientific Symposium on Ultrahigh Field Magnetic Resonance: Clinical Needs, Research Promises and Technical Solutions
Place of Event: Berlin, Germany
Start-/End Date: 2020-09-03 - 2020-09-04

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Title: 11th Annual Scientific Symposium on Ultrahigh Field Magnetic Resonance: Clinical Needs, Research Promises and Technical Solutions
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: P54 Start / End Page: 55 - 57 Identifier: -