English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Silver(I) Complexes with Camphorsulfonato and Phosphine Ligands: Structural Diversity and Antibacterial Activity

Kuchar, J., Rust, J., Lehmann, C. W., & Mohr, F. (2020). Silver(I) Complexes with Camphorsulfonato and Phosphine Ligands: Structural Diversity and Antibacterial Activity. Inorganic Chemistry, 59(15), 10557-10568. doi:10.1021/acs.inorgchem.0c00982.

Item is

Basic

show hide
Genre: Journal Article

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Kuchar, Julia1, Author
Rust, Jörg2, Author              
Lehmann, Christian W.2, Author              
Mohr, Fabian1, Author
Affiliations:
1Fakultät für Mathematik und Naturwissenschaften, Anorganische Chemie, Bergische Universität Wuppertal, Gaußstraße 20, 42119 Wuppertal, Germany, ou_persistent22              
2Service Department Lehmann (EMR), Max-Planck-Institut für Kohlenforschung, Max Planck Society, ou_1445625              

Content

show
hide
Free keywords: -
 Abstract: A series of silver(I) camphorsulfonato complexes containing various phosphine ligands having the stoichiometry [Ag(camphSO3)(PR3)] [PR3 = PTA (1,3,5-triaza-7-phosphaadamantane), PASO2 (2-thia-1,3,5-triaza-7-phosphaadamantane-2,2-dioxide), PPh3, PCy3, P(CH2CH2CN)3, PPyPh2, or P(o-tol)3] were prepared and fully characterized by NMR spectroscopic methods and X-ray crystallography. Depending on the nature of the phosphine, a variety of different supramolecular structures, including dimers, macrocycles, and coordination polymers, were observed in the solid state. The in vitro antimicrobial activity in seven different pathogens (Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter baumannii, Candida albicans, and Cryptococcus neoformans var. grubii) as well as toxicity in human cells was also examined. While all compounds show some activity against the bacteria, they were especially active against the fungus C. neoformans. The most active and at the same time least toxic compound was found to be the water-soluble complex [Ag(camphSO3)(PTA)2].

Details

show
hide
Language(s): eng - English
 Dates: 2020-04-022020-07-132020-08-03
 Publication Status: Published in print
 Pages: 12
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1021/acs.inorgchem.0c00982
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Inorganic Chemistry
  Abbreviation : Inorg. Chem.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Washington, DC : American Chemical Society
Pages: - Volume / Issue: 59 (15) Sequence Number: - Start / End Page: 10557 - 10568 Identifier: ISSN: 0020-1669
CoNE: https://pure.mpg.de/cone/journals/resource/0020-1669