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  Smartphone‐based multimodal tethered capsule endoscopic platform for white‐light, narrow‐band, and fluorescence/autofluorescence imaging

Sharma, G., Thoma, O.-M., Blessing, K., Gall, R., Waldner, M., & Singh, K. (2020). Smartphone‐based multimodal tethered capsule endoscopic platform for white‐light, narrow‐band, and fluorescence/autofluorescence imaging. Journal of Biophotonics, 14: e202000324. doi:10.1002/jbio.202000324.

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This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. © 2020 The Authors. Journal of Biophotonics published by Wiley-VCH GmbH.

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 Creators:
Sharma, Gargi1, Author           
Thoma, Oana-Maria2, 3, Author
Blessing, Katharina1, 4, Author           
Gall, Robert5, Author           
Waldner, Maximilian2, 3, Author
Singh, Kanwarpal1, 4, 6, Author           
Affiliations:
1Singh Research Group, Research Groups, Max Planck Institute for the Science of Light, Max Planck Society, ou_3164411              
2Department of Medicine 1, Friedrich- Alexander-Universität Erlangen- Nürnberg, Ulmenweg 18, 91054, Erlangen, Germany, ou_persistent22              
3Erlangen Graduate School of Advanced Optical Technologies (SAOT), Friedrich Alexander University Erlangen-Nürnberg, Erlangen, Germany, ou_persistent22              
4Department of Physics, Friedrich- Alexander Universität Erlangen- Nürnberg, Staudtstraße 7, 91058 Erlangen, Germany, ou_persistent22              
5Max Planck Institute for the Science of Light, Max Planck Society, ou_2355696              
6Max-Planck-Zentrum für Physik und Medizin, Max Planck Institute for the Science of Light, Max Planck Society, ou_3164414              

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Free keywords: Low-cost endoscopy; White-light imaging; Narrowband imaging; Fluorescence/autofluorescence imaging
 Abstract: Multimodal low‐cost endoscopy is highly desirable in poor resource settings such as in developing nations. In this work, we developed a smartphone‐based low‐cost, reusable tethered capsule endoscopic platform that allows white‐light, narrowband, and fluorescence/autofluorescence imaging of the esophagus. The ex‐vivo studies of swine esophagus were performed and compared with a commercial endoscope to test the white‐light imaging capabilities of the endoscope. The efficacy of the capsule for narrow‐band imaging was tested by imaging the vascularization of the tongue. To determine the autofluorescence/fluorescence capability of the endoscope, fluorescein dye with different concentrations was imaged. Furthermore, swine esophagus injected with fluorescein dye was imaged using the fluorescence/autofluorescence and the white‐light imaging modules, ex‐vivo. The overall cost of the capsules is approximately 12 €, 15 €, and 42 € for the white light imaging, the narrow‐band imaging, and the fluorescence/autofluorescence imaging respectively. In addition, the cost of the laser source module required for the narrow‐band imaging and the fluorescence/autofluorescence imaging is approximately 218 €. This device will open the possibility of imaging the esophagus in underprivileged areas.

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Language(s): eng - English
 Dates: 2020-08-122020-10-282020-11-01
 Publication Status: Published online
 Pages: 10
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1002/jbio.202000324
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Title: Journal of Biophotonics
Source Genre: Journal
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Publ. Info: John Wiley & Sons, Inc.
Pages: - Volume / Issue: 14 Sequence Number: e202000324 Start / End Page: - Identifier: -