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  Surface patterning for the control of receptor clustering and molecular forces of integrin-mediated adhesions

Pennarola, F., & Cavalcanti-Adam, E. A. (2021). Surface patterning for the control of receptor clustering and molecular forces of integrin-mediated adhesions. In M. Vicente-Manzanares (Ed.), The Integrin Interactome (pp. 183-195). New York, NY: Humana Press. doi:10.1007/978-1-0716-0962-0_11.

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Item Permalink: https://hdl.handle.net/21.11116/0000-0007-7257-7 Version Permalink: https://hdl.handle.net/21.11116/0000-0007-7258-6
Genre: Book Chapter

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MethMolBiol_2217_2021_183.pdf (Any fulltext), 2MB
 
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https://link.springer.com/content/pdf/10.1007%2F978-1-0716-0962-0_11.pdf (Any fulltext)
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 Creators:
Pennarola, Federica1, Author           
Cavalcanti-Adam, Elisabetta Ada1, Author           
Affiliations:
1Cellular Biophysics, Max Planck Institute for Medical Research, Max Planck Society, ou_2364731              

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Free keywords: Block copolymer micellar nanolithography, Nanopatterns, Integrins, Focal adhesions, Molecular tension sensors, Integrative tension sensors
 Abstract: Surface nanopatterning allows for the creation of spatially controlled binding sites for extracellular matrix
ligands and the modulation of receptor binding sites. Here we describe the preparation of gold nanopatterned
substrates using diblock micellar nanolithography to immobilize integrin ligands at defined spacing
and combined with molecular tension sensors to measure molecular forces as function of integrin lateral
clustering.

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Language(s): eng - English
 Dates: 2020-11-202021-01-01
 Publication Status: Issued
 Pages: 13
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1007/978-1-0716-0962-0_11
 Degree: -

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Title: The Integrin Interactome
Source Genre: Book
 Creator(s):
Vicente-Manzanares, Miguel, Editor
Affiliations:
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Publ. Info: New York, NY : Humana Press
Pages: - Volume / Issue: - Sequence Number: - Start / End Page: 183 - 195 Identifier: ISBN: 978-1-0716-0961-3

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Title: Methods in Molecular Biology
Source Genre: Series
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Publ. Info: New York, NY : Humana Press
Pages: - Volume / Issue: 2217 Sequence Number: - Start / End Page: - Identifier: ISSN: 1064-3745