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  Relation between chemotaxis and consumption of amino acids in bacteria

Yang, Y., Pollard, A. M., Hofler, C., Poschet, G., Wirtz, M., Hell, R., et al. (2015). Relation between chemotaxis and consumption of amino acids in bacteria. Molecular Microbiology, 96(6), 1272-1282. doi:10.1111/mmi.13006.

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Yang, Y.1, Autor           
Pollard, A. M.1, Autor           
Hofler, C., Autor
Poschet, G., Autor
Wirtz, M., Autor
Hell, R., Autor
Sourjik, V.1, 2, 3, Autor           
Affiliations:
1Microbial Networks, Department of Systems and Synthetic Microbiology, Max Planck Institute for Terrestrial Microbiology, Max Planck Society, ou_3266309              
2Center for Synthetic Microbiology (SYNMIKRO), ou_persistent22              
3DKFZ-ZMBH Alliance, Centre for Molecular Biology, Heidelberg, ou_persistent22              

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 Zusammenfassung: Chemotaxis enables bacteria to navigate chemical gradients in their environment, accumulating toward high concentrations of attractants and avoiding high concentrations of repellents. Although finding nutrients is likely to be an important function of bacterial chemotaxis, not all characterized attractants are nutrients. Moreover, even for potential nutrients, the exact relation between the metabolic value of chemicals and their efficiency as chemoattractants has not been systematically explored. Here we compare the chemotactic response of amino acids with their use by bacteria for two well-established models of chemotactic behavior, Escherichia coli and Bacillus subtilis. We demonstrate that in E. coli chemotaxis toward amino acids indeed strongly correlates with their utilization. However, no such correlation is observed for B. subtilis, suggesting that in this case, the amino acids are not followed because of their nutritional value but rather as environmental cues.

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 Datum: 2015-06
 Publikationsstatus: Erschienen
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 Ort, Verlag, Ausgabe: -
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 Art der Begutachtung: Interne Begutachtung
 Identifikatoren: eDoc: 717103
ISI: 000356000900011
DOI: 10.1111/mmi.13006
 Art des Abschluß: -

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Titel: Molecular Microbiology
Genre der Quelle: Zeitschrift
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Ort, Verlag, Ausgabe: -
Seiten: - Band / Heft: 96 (6) Artikelnummer: - Start- / Endseite: 1272 - 1282 Identifikator: ISSN: 0950-382X