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  Primary structure and functional expression from complementary DNA of the rod photoreceptor cyclic GMP-gated channel

Kaupp, U. B., Niidome, T., Tanabe, T., Terada, S., Bönigk, W., Stuehmer, W., et al. (1989). Primary structure and functional expression from complementary DNA of the rod photoreceptor cyclic GMP-gated channel. Nature, 342(6251), 762-766. doi:10.1038/342762a0.

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 Creators:
Kaupp, Ulrich Benjamin1, Author
Niidome, Tetsuhiro2, Author
Tanabe, Tsutomu2, Author
Terada, Shoichi2, Author
Bönigk, Wolfgang1, Author
Stuehmer, Walther3, Author           
Cook, Neil J.4, 5, Author           
Kangawa, Kenji6, Author
Matsuo, Hisayuki6, Author
Hirose, Tadaaki7, Author
Miyata, Takashi8, Author
Numa, Shosaku2, Author
Affiliations:
1Institut für Biologische Informationsverarbeitung, Kernforschungsanlage, 5170 Jülich, Germany, ou_persistent22              
2Departments of Medical Chemistry and Molecular Genetics, Kyoto University Faculty of Medicine, Kyoto 606, Japan, ou_persistent22              
3Department of Membrane Biophysics, MPI for biophysical chemistry, Max Planck Society, ou_578579              
4Department of Molecular Membrane Biology, Max Planck Institute of Biophysics, Max Planck Society, ou_2068290              
5Abteilung Biophysik, Universität Osnabrück, D-4500 Osnabrück, Germany, ou_persistent22              
6Department of Biochemistry, Miyazaki Medical College, Miyazaki 889-16, Japan, ou_persistent22              
7Pharmaceutical Institute, Keio University School of Medicine, Tokyo 160, Japan, ou_persistent22              
8Department of Biology, Kyushu University Faculty of Science, Fukuoka 812, Japan, ou_persistent22              

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 Abstract: The complete amino-acid sequence of the cyclic GMP-gated channel from bovine retinal rod photo-receptors, deduced by cloning and sequencing its complementary DNA, shows that the protein contains several putative transmembrane segments, followed by a region that is similar to the cyclic GMP-binding domains of cyclic GMP-dependent protein kinase. Expression of the complementary DNA produces cyclic GMP-gated channel activity in Xenopus oocytes

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Language(s): eng - English
 Dates: 1989-09-081989-10-081989-12-14
 Publication Status: Issued
 Pages: 5
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1038/342762a0
PMID: 2481236
 Degree: -

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Title: Nature
  Abbreviation : Nature
Source Genre: Journal
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Publ. Info: London : Nature Publishing Group
Pages: - Volume / Issue: 342 (6251) Sequence Number: - Start / End Page: 762 - 766 Identifier: ISSN: 0028-0836
CoNE: https://pure.mpg.de/cone/journals/resource/954925427238