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  Components of a Neanderthal gut microbiome recovered from fecal sediments from El Salt

Rampelli, S., Turroni, S., Mallol, C., Hernandez, C., Galván, B., Sistiaga, A., et al. (2021). Components of a Neanderthal gut microbiome recovered from fecal sediments from El Salt. Communications Biology, 4(1): 169, pp. 1-10. Retrieved from 10.1038/s42003-021-01689-y.

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Supplementary information, Data 1-3, Reporting summary, etc. (Ergänzendes Material)
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(last seen: Feb. 2021)
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 Urheber:
Rampelli, Simone, Autor
Turroni, Silvia, Autor
Mallol, Carolina, Autor
Hernandez, Cristo, Autor
Galván, Bertila, Autor
Sistiaga, Ainara, Autor
Biagi, Elena, Autor
Astolfi, Annalisa, Autor
Brigidi, Patrizia, Autor
Benazzi, Stefano, Autor
Lewis, Cecil M., Autor
Warinner, Christina1, 2, Autor           
Hofman, Courtney A., Autor
Schnorr, Stephanie L., Autor
Candela, Marco, Autor
Affiliations:
1Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society, ou_2074310              
2Kostbare Kulturen, Max Planck Institute for the Science of Human History, Max Planck Society, ou_2591692              

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Schlagwörter: Metagenomics, Microbial ecology, Microbiome
 Zusammenfassung: A comprehensive view of our evolutionary history cannot ignore the ancestral features of our gut microbiota. To provide some glimpse into the past, we searched for human gut microbiome components in ancient DNA from 14 archeological sediments spanning four stratigraphic units of El Salt Middle Paleolithic site (Spain), including layers of unit X, which has yielded well-preserved Neanderthal occupation deposits dating around 50 kya. According to our findings, bacterial genera belonging to families known to be part of the modern human gut microbiome are abundantly represented only across unit X samples, showing that well-known beneficial gut commensals, such as Blautia, Dorea, Roseburia, Ruminococcus, Faecalibacterium and Bifidobacterium already populated the intestinal microbiome of Homo since as far back as the last common ancestor between humans and Neanderthals.

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Sprache(n): eng - English
 Datum: 2021-02-05
 Publikationsstatus: Online veröffentlicht
 Seiten: 10
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: Results and discussion
- Ancient DNA sequencing and damage assessment.
- Detection of ancient human mitochondrial DNA.
- Profiling of ancient prokaryotic DNA.
- Putative components of the Neanderthal gut microbiome.
Methods
- Site and sampling.
- Ancient DNA extraction.
- Library preparation and sequencing.
- Bioinformatics analysis.
- Independent validation of taxonomic assignments.
- mtDNA analysis and contamination estimate.
- Statistics and reproducibility.
 Art der Begutachtung: Expertenbegutachtung
 Identifikatoren: URI: 10.1038/s42003-021-01689-y
Anderer: shh2851
 Art des Abschluß: -

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Titel: Communications Biology
Genre der Quelle: Zeitschrift
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Ort, Verlag, Ausgabe: London : Springer Nature
Seiten: - Band / Heft: 4 (1) Artikelnummer: 169 Start- / Endseite: 1 - 10 Identifikator: ISSN: 2399-3642
CoNE: https://pure.mpg.de/cone/journals/resource/2399-3642