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  Conceptual analysis: A Social neuroscience approach to interpersonal interaction in the context of disruption and disorganization of attachment (NAMDA)

White, L. O., Schulz, C., Schoett, M. J. S., Kungl, M. T., Keil, J., Borelli, J. L., et al. (2020). Conceptual analysis: A Social neuroscience approach to interpersonal interaction in the context of disruption and disorganization of attachment (NAMDA). Frontiers in Psychiatry, 11: 517372. doi:10.3389/fpsyt.2020.517372.

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White, Lars O.1, Author
Schulz, Charlotte1, 2, Author           
Schoett, Margerete J. S.1, Author
Kungl, Melanie T.3, Author
Keil, Jan1, Author
Borelli, Jessica L.4, Author
Vrticka, Pascal5, 6, Author           
1Department of Child and Adolescent Psychiatry, Psychotherapy, and Psychosomatics, University of Leipzig, Germany, ou_persistent22              
2Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634549              
3Institute of Psychology, Friedrich Alexander University Erlangen, Germany, ou_persistent22              
4Department of Psychology and Social Behavior, University of California, Irvine, CA, USA, ou_persistent22              
5Research Group Social Stress and Family Health, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_3025667              
6Department of Psychology, University of Essex, Colchester, United Kingdom, ou_persistent22              


Free keywords: Co-regulation; Disorganized attachment; Maltreatment; Neglect and abuse; Social interaction; Social neuroscience
 Abstract: Humans are strongly dependent upon social resources for allostasis and emotion regulation. This applies especially to early childhood because humans-as an altricial species-have a prolonged period of dependency on support and input from caregivers who typically act as sources of co-regulation. Accordingly, attachment theory proposes that the history and quality of early interactions with primary caregivers shape children's internal working models of attachment. In turn, these attachment models guide behavior, initially with the set goal of maintaining proximity to caregivers but eventually paving the way to more generalized mental representations of self and others. Mounting evidence in non-clinical populations suggests that these mental representations coincide with differential patterns of neural structure, function, and connectivity in a range of brain regions previously associated with emotional and cognitive capacities. What is currently lacking, however, is an evidence-based account of how early adverse attachment-related experiences and/or the emergence of attachment disorganization impact the developing brain. While work on early childhood adversities offers important insights, we propose that how these events become biologically embedded crucially hinges on the context of the child-caregiver attachment relationships in which the events take place. Our selective review distinguishes between direct social neuroscience research on disorganized attachment and indirect maltreatment-related research, converging on aberrant functioning in neurobiological systems subserving aversion, approach, emotion regulation, and mental state processing in the wake of severe attachment disruption. To account for heterogeneity of findings, we propose two distinct neurobiological phenotypes characterized by hyper- and hypo-arousal primarily deriving from the caregiver serving either as a threatening or as an insufficient source of co-regulation, respectively.


Language(s): eng - English
 Dates: 2019-12-192020-11-182020-12-23
 Publication Status: Published online
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.3389/fpsyt.2020.517372
Other: eCollection 2020
PMID: 33424647
PMC: PMC7785824
 Degree: -



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Project name : -
Grant ID : 01KR1201A to E
Funding program : -
Funding organization : German Federal Ministry of Education and Research (BMBF)
Project name : -
Grant ID : 100316844
Funding program : European Social Fund (ESF)
Funding organization : European Union and the Free State of Saxony
Project name : -
Grant ID : -
Funding program : -
Funding organization : Max Planck Society
Project name : LIFE - Leipzig Research Center for Civilization Diseases, University of Leipzig
Grant ID : -
Funding program : -
Funding organization : European Union, the European Regional Development Fund (ERDF), and the Free State of Saxony

Source 1

Title: Frontiers in Psychiatry
  Abbreviation : Front Psychiatry
Source Genre: Journal
Publ. Info: Lausanne, Switzerland : Frontiers Research Foundation
Pages: - Volume / Issue: 11 Sequence Number: 517372 Start / End Page: - Identifier: ISSN: 1664-0640
CoNE: https://pure.mpg.de/cone/journals/resource/16640640