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  Does sphingomyelin inhibit the erythrocyte anion transport system?

Scheuring, U., Haase, W., & Schubert, D. (1988). Does sphingomyelin inhibit the erythrocyte anion transport system? FEBS Letters, 231(1), 232-236. doi:10.1016/0014-5793(88)80738-5.

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 Creators:
Scheuring, Uwe1, Author           
Haase, Winfried2, Author           
Schubert, Dieter1, Author           
Affiliations:
1Department of Cell Physiology, Max Planck Institute of Biophysics, Max Planck Society, ou_3264817              
2Department of Physiology, Max Planck Institute of Biophysics, Max Planck Society, ou_2068297              

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Free keywords: Sphingomyelin; Anion transport; Band 3 protein; Reconstitution, (Erythrocyte membrane); SPH, sphingomyelin; PC, phosphatidylcholine; H2DIDS, 4′-diisothiocyanostilbene-2,2′-disulfonate
 Abstract: The anion transport protein of the human erythrocyte membrane, band 3, was incorporated into unilamellar sphingomyelin vesicles. The vesicles showed a rapid sulfate efflux which could be inhibited by specific inhibitors of the erythrocyte anion transport system. All band 3 molecules contributing to the inhibitor-sensitive flux component were arranged 'right-side-out'. The turnover number of the transport protein for sulfate transport was virtually identical to that in phosphatidylcholine bilayers and around 6 times larger than in human erythrocyte membranes. Thus, in contrast to other claims, sphingomyelin does not inhibit the erythrocyte anion transport system.

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Language(s): eng - English
 Dates: 1988-02-221987-12-212001-10-191988-04-11
 Publication Status: Published in print
 Pages: 5
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1016/0014-5793(88)80738-5
PMID: 3360128
 Degree: -

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Title: FEBS Letters
  Other : FEBS Lett.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Amsterdam : Elsevier
Pages: - Volume / Issue: 231 (1) Sequence Number: - Start / End Page: 232 - 236 Identifier: ISSN: 0014-5793
CoNE: https://pure.mpg.de/cone/journals/resource/954925399501