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Free keywords:
Xenopus; Oocyte; Cotransport; Alanine flux; Sodium current; Sodium activity; Membrane potential
Abstract:
During progesterone-induced maturation of oocytes of Xenopus laevis the fast decrease of the rate of Na+-alanine cotransport is accompanied by a depolarization of the membrane potential and an increase in the intracellular Na+ activity. It is demonstrated that the decrease of the Na+-dependent alanine uptake is the result of the depolarization while the simultaneous increase in intracellular Na+ activity has no significant effect.