English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Cellular and Genomic Properties of Haloferax gibbonsii LR2-5, the Host of Euryarchaeal Virus HFTV1

Tittes, C., Schwarzer, S., Pfeiffer, F., Dyall-Smith, M., Rodriguez-Franco, M., Oksanen, H. M., et al. (2021). Cellular and Genomic Properties of Haloferax gibbonsii LR2-5, the Host of Euryarchaeal Virus HFTV1. Frontiers in Microbiology, 12: 625599. doi:10.3389/fmicb.2021.625599.

Item is

Basic

show hide
Genre: Journal Article

Files

show Files
hide Files
:
fmicb-12-625599.pdf (Publisher version), 3MB
Name:
fmicb-12-625599.pdf
Description:
-
Visibility:
Public
MIME-Type / Checksum:
application/pdf / [MD5]
Technical Metadata:
Copyright Date:
-
Copyright Info:
© 2021 Tittes, Schwarzer, Pfeiffer, Dyall-Smith, Rodriguez-Franco, Oksanen and Quax.
:
5306240.zip (Supplementary material), 22MB
Name:
5306240.zip
Description:
-
Visibility:
Public
MIME-Type / Checksum:
application/zip / [MD5]
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show

Creators

show
hide
 Creators:
Tittes, Colin1, Author
Schwarzer, Sabine1, Author
Pfeiffer, Friedhelm2, Author              
Dyall-Smith, Mike2, Author              
Rodriguez-Franco, Marta1, Author
Oksanen, Hanna M.1, Author
Quax, Tessa E. F.1, Author
Affiliations:
1external, ou_persistent22              
2Habermann, Bianca / Computational Biology, Max Planck Institute of Biochemistry, Max Planck Society, ou_1832284              

Content

show
hide
Free keywords: Microbiology; haloarchaea; archaeal virus; type IV pili; S-layer; archaellum; N-glycosylation;
 Abstract: Hypersaline environments are the source of many viruses infecting different species of halophilic euryarchaea. Information on infection mechanisms of archaeal viruses is scarce, due to the lack of genetically accessible virus-host models. Recently, a new archaeal siphovirus, Haloferax tailed virus 1 (HFTV1), was isolated together with its host belonging to the genus Haloferax, but it is not infectious on the widely used model euryarcheon Haloferax volcanii. To gain more insight into the biology of HFTV1 host strain LR2-5, we studied characteristics that might play a role in its virus susceptibility: growth-dependent motility, surface layer, filamentous surface structures, and cell shape. Its genome sequence showed that LR2-5 is a new strain of Haloferax gibbonsii. LR2-5 lacks obvious viral defense systems, such as CRISPR-Cas, and the composition of its cell surface is different from Hfx. volcanii, which might explain the different viral host range. This work provides first deep insights into the relationship between the host of halovirus HFTV1 and other members of the genus Haloferax. Given the close relationship to the genetically accessible Hfx. volcanii, LR2-5 has high potential as a new model for virus-host studies in euryarchaea.

Details

show
hide
Language(s): eng - English
 Dates: 2021
 Publication Status: Published online
 Pages: 14
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: ISI: 000623995000001
DOI: 10.3389/fmicb.2021.625599
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Frontiers in Microbiology
  Abbreviation : Front. Microbiol.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Lausanne : Frontiers Media
Pages: - Volume / Issue: 12 Sequence Number: 625599 Start / End Page: - Identifier: ISSN: 1664-302X
CoNE: https://pure.mpg.de/cone/journals/resource/1664-302X