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  Molecular cloning of substance P receptor cDNA from guinea-pig uterus

Gorbulev, V., Akhundova, A., Luzius, H., & Fahrenholz, F. (1992). Molecular cloning of substance P receptor cDNA from guinea-pig uterus. Biochimica et Biophysica Acta-Gene Structure and Expression, 1131(1), 99-102. doi:10.1016/0167-4781(92)90105-9.

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Item Permalink: https://hdl.handle.net/21.11116/0000-0008-32AF-B Version Permalink: https://hdl.handle.net/21.11116/0000-0008-32B0-8
Genre: Journal Article

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 Creators:
Gorbulev, Valentin1, Author           
Akhundova, Aida1, Author           
Luzius, Heike1, Author           
Fahrenholz, Falk1, Author           
Affiliations:
1Emeritusgroup Physical Chemistry, Max Planck Institute of Biophysics, Max Planck Society, ou_3273414              

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Free keywords: Substance P receptor; G-protein-coupled receptor; Guinea-pig uterus; COS cell expression
 Abstract: A cDNA encoding guinea-pig uterine substance P (SP) receptor has been isolated using the homology screening approach. Northern blot analysis reveals that the corresponding mRNA, of approx. 4.8 kb, is expressed in all tissues tested, but predominantly in the uteri of non-pregnant animals; during pregnancy its expression is reduced. The guinea-pig SP receptor was expressed in COS-7 cells and demonstrated relative ligand affinity in the order: SP ⪢ neurokinin A > neurokinin B.

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Language(s): eng - English
 Dates: 1991-03-032003-01-241992-05-07
 Publication Status: Issued
 Pages: 4
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1016/0167-4781(92)90105-9
PMID: 1374648
 Degree: -

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Title: Biochimica et Biophysica Acta-Gene Structure and Expression
  Other : Biochim. Biophys. Acta-Gene Struct. Expression
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: New York, NY : Elsevier
Pages: - Volume / Issue: 1131 (1) Sequence Number: - Start / End Page: 99 - 102 Identifier: ISSN: 0167-4781
CoNE: https://pure.mpg.de/cone/journals/resource/954926938702_1