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  Mixing “good and bad” annoys neutrophils

Trompouki, E. (2021). Mixing “good and bad” annoys neutrophils. Blood, 137, 1272-1274. doi:10.1182/blood.2020009854.

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Trompouki 2021.pdf (Publisher version), 784KB
 
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Trompouki, Eirini1, Author              
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1Department of Cellular and Molecular Immunology, Max Planck Institute of Immunobiology and Epigenetics, Max Planck Society, ou_2243641              

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 Abstract: In this issue of Blood, Schürch et al show that signal recognition particle 54 (SRP54) mutations found in patients with congenital neutropenia act in a dominant-negative manner on the functionality of the wild-type SRP54, leading to neutropenia because of impaired splicing of the transcription factor X-box binding protein 1 (XBP1).

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Language(s): eng - English
 Dates: 2021-03-11
 Publication Status: Published online
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 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1182/blood.2020009854
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Title: Blood
  Other : Blood
Source Genre: Journal
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Publ. Info: Philadelphia, Pa. : W.B. Saunders
Pages: - Volume / Issue: 137 Sequence Number: - Start / End Page: 1272 - 1274 Identifier: ISSN: 0006-4971
CoNE: https://pure.mpg.de/cone/journals/resource/954925385125