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  pH-dependence of phosphate absorption in rat renal proximal tubule

Samaržija, I., Molnar, V., & Frömter, E. (1983). pH-dependence of phosphate absorption in rat renal proximal tubule. Proceedings of the European Dialysis and Transplant Association, 19, 779-783.

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 Urheber:
Samaržija, Ita1, 2, Autor           
Molnar, Vieroslav2, Autor
Frömter, Eberhard1, Autor           
Affiliations:
1Department of Physiology, Max Planck Institute of Biophysics, Max Planck Society, ou_2068297              
2Centar zu Hemodijalizu i Nefrologiju, P. Miskina 64, YU-41000, Zagreb, Yugoslavia, ou_persistent22              

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 Zusammenfassung: Proximal tubular cell membrane potentials were measured in rat kidney in vivo and the response to luminal perfusion of 2mmolar phosphate (Pi) was studied. Pi transport was preferentially rheogenic at low pH (cotransport of 1H2PO4- plus 2Na+) but preferentially electroneutral at high pH (cotransport of 1HPO4-- plus 2Na+). The potential response as a function of pH conformed to a model which transports both H2PO4- and HPO4-- indiscriminately and whose maximal transport capacity increases with increasing pH. Further kinetic experiments are required to definitely exclude separate transport systems for both ionised forms. Hypercapnic phosphaturia may be explained by a decreased maximal transport capacity of Pi at low luminal pH.

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Sprache(n): eng - English
 Datum: 1983-01-01
 Publikationsstatus: Erschienen
 Seiten: 5
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: Expertenbegutachtung
 Identifikatoren: PMID: 6878264
 Art des Abschluß: -

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Titel: Proceedings of the European Dialysis and Transplant Association
  Kurztitel : Proc Eur Dial Transplant Assoc
Genre der Quelle: Zeitschrift
 Urheber:
Affiliations:
Ort, Verlag, Ausgabe: London, England : Pitman Publishing
Seiten: - Band / Heft: 19 Artikelnummer: - Start- / Endseite: 779 - 783 Identifikator: ISSN: 0071-2736