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  Phosphate Transport by Isolated Renal and Intestinal Plasma Membranes

Kinne, R., Berner, W., Hoffmann, N., & Murer, H. (1977). Phosphate Transport by Isolated Renal and Intestinal Plasma Membranes. In S. G. Massry, & E. Ritz (Eds.), Phosphate Metabolism. Advances in Experimental Medicine and Biology (pp. 265-277). New York: Springer Science+Business Media 1977. doi:10.1007/978-1-4613-4217-5_26.

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Datensatz-Permalink: https://hdl.handle.net/21.11116/0000-0009-80D3-7 Versions-Permalink: https://hdl.handle.net/21.11116/0000-0009-80D4-6
Genre: Buchkapitel

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Urheber

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 Urheber:
Kinne, Rolf1, Autor           
Berner, Winfried1, Autor           
Hoffmann, N.1, Autor           
Murer, Heini1, Autor           
Affiliations:
1Department of Physiology, Max Planck Institute of Biophysics, Max Planck Society, ou_2068297              

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Schlagwörter: -
 Zusammenfassung: Studies of luminal and contraluminal membranes isolated from epithelial cells have contributed markedly to our understanding of the molecular mechanisms, the driving forces and the sequence of events involved in transcellular transport of solutes. They were extended recently to investigate the properties of phosphate transport systems in renal and intestinal brush border and basal-lateral plasma membrane vesicles. The investigations revealed that both in the renal proximal tubule and in the small intestine the luminal membranes but not the contraluminal membranes contain a sodium-phosphate cotransport system. This suggests that the driving force for the transcellular phosphate movement is derived from the sodium gradient present and maintained across the brush border membrane. The importance of the sodium cotransport system for the active phosphate reabsorption in the proximal tubule is further indicated by the fact that parathyroid hormone (PTH), which decreases the phosphate reabsorption in the renal proximal tubule also reduces the capacity of the sodium-phosphate cotransport system in isolated renal brush border microvilli

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Sprache(n): eng - English
 Datum: 2013-06-221977
 Publikationsstatus: Erschienen
 Seiten: 18
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: Expertenbegutachtung
 Identifikatoren: DOI: 10.1007/978-1-4613-4217-5_26
PMID: 19947
 Art des Abschluß: -

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Titel: Phosphate Metabolism. Advances in Experimental Medicine and Biology
Genre der Quelle: Reihe
 Urheber:
Massry, Shaul G.1, Herausgeber
Ritz, Eberhard2, Herausgeber
Affiliations:
1 University of Southern California, Los Angeles, USA, ou_persistent22            
2 Department of Internal Medicine, University of Heidelberg, Heidelberg, Germany, ou_persistent22            
Ort, Verlag, Ausgabe: New York : Springer Science+Business Media 1977
Seiten: 636 Band / Heft: 81 Artikelnummer: - Start- / Endseite: 265 - 277 Identifikator: ISBN: 978-1-4613-4219-9
ISBN: 978-1-4613-4217-5
DOI: 10.1007/978-1-4613-4217-5