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Free keywords:
Biological Transport, Ion Channels, Mathematics, Models, Theoretical, Particle Size
Abstract:
We study the distribution of direct translocation times for particles passing through membrane channels connecting two reservoirs. The direct translocation time is a conditional first-passage time defined as the residence time of the particle in the channel while passing to the other side of the membrane directly, i.e., without returning to the reservoir from which it entered. We show that the distributions of direct translocation times are identical for translocation in both directions, independent of any asymmetry in the potential across the channel and, hence, the translocation probabilities.
