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  ProFit-v3: accuracy and precision evaluation of a new spectral fitting software

Borbath, T., Murali-Manohar, S., Dorst, J., Wright, A., & Henning, A. (2021). ProFit-v3: accuracy and precision evaluation of a new spectral fitting software. Poster presented at 2021 ISMRM & SMRT Annual Meeting & Exhibition (ISMRM 2021).

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Borbath, T1, 2, Author              
Murali-Manohar, S1, 2, Author              
Dorst, J1, 2, Author              
Wright, AM1, 2, Author              
Henning, A1, 2, Author              
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1Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_2528692              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              

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 Abstract: In this work, we present the newly developed MRS fitting software ProFit-v3, including adaptive baseline stiffness control and a newly proposed cost function calculation. ProFit-v3 was evaluated for accuracy and precision using both simulated and in vivo spectra, and the results were compared against LCModel. The adaptive spline baseline model of ProFit-v3 modelled different simulated baseline distortions well. The fitting accuracy measured on simulated data was slightly better for ProFit-v3 than for LCModel. While the fitting precision of ProFit-v3 was comparable to that of LCModel for the simulated data, LCModel proved to be somewhat more precise for in vivo spectra.

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 Dates: 2021-05
 Publication Status: Published online
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Title: 2021 ISMRM & SMRT Annual Meeting & Exhibition (ISMRM 2021)
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Start-/End Date: 2021-05-15 - 2021-05-20

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Title: 2021 ISMRM & SMRT Annual Meeting & Exhibition (ISMRM 2021)
Source Genre: Proceedings
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