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Abstract:
The thalamus is a central connectivity hub of the human brain that remains poorly understood concerning its anatomy. Since it houses both calcium-rich neurons and myelin-rich architecture, quantitative susceptibility mapping at the ultra-high-field may facilitate thalamic substructures' characterization. Consequently, we have acquired high-resolution QSM data at 9.4 Tesla in 21 subjects and analyzed human thalamic nuclei with respect to core and matrix neurons. We found a more substantial contribution of both diamagnetic and paramagnetic sources, like iron, myelin, and calcium, in the matrix nuclei in contrast to the relay specific core nuclei matrix nuclei.
