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Schlagwörter:
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Zusammenfassung:
The type III secretion system is the common core of two bacterial
molecular machines: the flagellum and the injectisome. The flagellum is
the most widely distributed prokaryotic locomotion device, whereas the
injectisome is a syringe-like apparatus for inter-kingdom protein
translocation, which is essential for virulence in important human
pathogens. The successful concept of the type III secretion system has
been modified for different bacterial needs. It can be adapted to
changing conditions, and was found to be a dynamic complex constantly
exchanging components. In this review, we highlight the flexibility,
adaptivity, and dynamic nature of the type III secretion system.
