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  Molecular networks of the FOXP2 transcription factor in the brain

Den Hoed, J., Devaraju, K., & Fisher, S. E. (2021). Molecular networks of the FOXP2 transcription factor in the brain. EMBO Reports, 22(8): e52803. doi:10.15252/embr.202152803.

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Item Permalink: https://hdl.handle.net/21.11116/0000-0008-A453-1 Version Permalink: https://hdl.handle.net/21.11116/0000-0009-14D1-4
Genre: Journal Article

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DenHoed_Devaraju_Fisher_2021_Molecular networks of the FOXP2 transcription factor in the brain.pdf (Publisher version), 2MB
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DenHoed_Devaraju_Fisher_2021_Molecular networks of the FOXP2 transcription factor in the brain.pdf
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2021
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© 2021 The Authors. Published under the terms of the CC BY 4.0 license This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
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https://creativecommons.org/licenses/by/4.0/

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 Creators:
Den Hoed, Joery1, 2, Author           
Devaraju, Karthikeyan2, Author           
Fisher, Simon E.2, 3, Author           
Affiliations:
1International Max Planck Research School for Language Sciences, MPI for Psycholinguistics, Max Planck Society, ou_1119545              
2Language and Genetics Department, MPI for Psycholinguistics, Max Planck Society, ou_792549              
3Donders Institute for Brain, Cognition and Behaviour, External Organizations, ou_55236              

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 Abstract: The discovery of the FOXP2 transcription factor, and its implication in a rare severe human speech and language disorder, has led to two decades of empirical studies focused on uncovering its roles in the brain using a range of in vitro and in vivo methods. Here, we discuss what we have learned about the regulation of FOXP2, its downstream effectors, and its modes of action as a transcription factor in brain development and function, providing an integrated overview of what is currently known about the critical molecular networks.

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Language(s): eng - English
 Dates: 2021-06-042021-08
 Publication Status: Published online
 Pages: -
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 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.15252/embr.202152803
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Title: EMBO Reports
  Other : EMBO Rep.
Source Genre: Journal
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Publ. Info: Oxford, UK
Pages: - Volume / Issue: 22 (8) Sequence Number: e52803 Start / End Page: - Identifier: ISSN: 1469-221X
CoNE: https://pure.mpg.de/cone/journals/resource/110978984569661