Deutsch
 
Hilfe Datenschutzhinweis Impressum
  DetailsucheBrowse

Datensatz

 
 
DownloadE-Mail
  Automated assembly of starch and glycogen polysaccharides

Zhu, Y., Delbianco, M., & Seeberger, P. H. (2021). Automated assembly of starch and glycogen polysaccharides. Journal of the American Chemical Society, 143(26), 9758-9768. doi:10.1021/jacs.1c02188.

Item is

Basisdaten

einblenden: ausblenden:
Genre: Zeitschriftenartikel

Dateien

einblenden: Dateien
ausblenden: Dateien
:
Article.pdf (Verlagsversion), 7MB
Name:
Article.pdf
Beschreibung:
-
OA-Status:
Hybrid
Sichtbarkeit:
Öffentlich
MIME-Typ / Prüfsumme:
application/pdf / [MD5]
Technische Metadaten:
Copyright Datum:
-
Copyright Info:
-

Externe Referenzen

einblenden:

Urheber

einblenden:
ausblenden:
 Urheber:
Zhu, Yuntao1, Autor           
Delbianco, Martina2, Autor           
Seeberger, Peter H.1, Autor           
Affiliations:
1Peter H. Seeberger - Automated Systems, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society, ou_1863306              
2Martina Delbianco, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society, ou_2559692              

Inhalt

einblenden:
ausblenden:
Schlagwörter: Carbohydrates; Protective groups; Organic compounds; Chemical biology; Post-translational modification
 Zusammenfassung: Polysaccharides are Nature’s most abundant biomaterials essential for plant cell wall construction and energy storage. Seemingly minor structural differences result in entirely different functions: cellulose, a β (1–4) linked glucose polymer, forms fibrils that can support large trees, while amylose, an α (1–4) linked glucose polymer forms soft hollow fibers used for energy storage. A detailed understanding of polysaccharide structures requires pure materials that cannot be isolated from natural sources. Automated Glycan Assembly provides quick access to trans-linked glycans analogues of cellulose, but the stereoselective installation of multiple cis-glycosidic linkages present in amylose has not been possible to date. Here, we identify thioglycoside building blocks with different protecting group patterns that, in concert with temperature and solvent control, achieve excellent stereoselectivity during the synthesis of linear and branched α-glucan polymers with up to 20 cis-glycosidic linkages. The molecules prepared with the new method will serve as probes to understand the biosynthesis and the structure of α-glucans.

Details

einblenden:
ausblenden:
Sprache(n): eng - English
 Datum: 2021-06-112021
 Publikationsstatus: Erschienen
 Seiten: -
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: -
 Identifikatoren: DOI: 10.1021/jacs.1c02188
BibTex Citekey: doi:10.1021/jacs.1c02188
 Art des Abschluß: -

Veranstaltung

einblenden:

Entscheidung

einblenden:

Projektinformation

einblenden:

Quelle 1

einblenden:
ausblenden:
Titel: Journal of the American Chemical Society
  Andere : JACS
  Kurztitel : J. Am. Chem. Soc.
Genre der Quelle: Zeitschrift
 Urheber:
Affiliations:
Ort, Verlag, Ausgabe: Washington, DC : American Chemical Society
Seiten: - Band / Heft: 143 (26) Artikelnummer: - Start- / Endseite: 9758 - 9768 Identifikator: ISSN: 0002-7863