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  Natural Peptide Lactones As Ion Carriers In Membranes

Oberbäumer, I., Feigl, P., Ruf, H., & Grell, E. (1981). Natural Peptide Lactones As Ion Carriers In Membranes. In W. Voelter (Ed.), Structure and Activity of Natural Peptides (pp. 349-362). Berlin, New York: Walter de Gruyter & Co.,. doi:10.1515/9783110861631-037.

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Genre: Conference Paper

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 Creators:
Oberbäumer, Ilse1, Author           
Feigl, Peter1, Author           
Ruf, Horst1, Author           
Grell, Ernst1, Author           
Affiliations:
1Molecular Biophysics Group, Max Planck Institute of Biophysics, Max Planck Society, ou_3264820              

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 Abstract: The streptogramins are a well-known family of antibiotics that are produced by several streptomycetes. According to their different structures these antibiotics have been classified into the two groups A and B. All members of group A are macrocyclic lactones while those of group B are peptide lac-tones containing six to seven amino acid residues in the ring. The structures of the three main components of group B are shown in Fig. 1. It has been generally accepted that the streptogramins of both groups interact with the bacterial 50 S ribosomal subunit and block protein biosynthesis. The A components interfere with the ribosomal peptidyl transferase, whereas the effect of the B components appears to be rather indirect.

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Language(s): eng - English
 Dates: 19802019-10-081981-05-01
 Publication Status: Published in print
 Pages: 15
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1515/9783110861631-037
 Degree: -

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Title: Proceedings of the Fall Meeting - Gesellschaft für Biologische Chemie
Place of Event: Tübingen, Germany
Start-/End Date: 1979-09 - 1979-09

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Title: Structure and Activity of Natural Peptides
  Subtitle : Selected Topics
Source Genre: Proceedings
 Creator(s):
Voelter, Wolfgang1, Editor
Weitzel, Günther2, Author
Affiliations:
1 Abteilung für Physikalische Biochemie, Universität Tübingen, Tübingen, Germany , ou_persistent22            
2 Physiologisch-chemisches Institut, Universität Tübingen, Tübingen, Germany, ou_persistent22            
Publ. Info: Berlin, New York : Walter de Gruyter & Co.,
Pages: 635 Volume / Issue: - Sequence Number: - Start / End Page: 349 - 362 Identifier: DOI: 10.1515/9783110861631
ISBN: 978-3110082647