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  α1-Adrenergic stimulation causes Mg2+ release from perfused rat liver

Jakob, A., Becker, J., Schöttli, G., & Fritzsch, G. (1989). α1-Adrenergic stimulation causes Mg2+ release from perfused rat liver. FEBS Letters, 246(1-2), 127-130. doi:10.1016/0014-5793(89)80267-4.

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Item Permalink: https://hdl.handle.net/21.11116/0000-0008-E3F1-7 Version Permalink: https://hdl.handle.net/21.11116/0000-0008-E3F2-6
Genre: Journal Article

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 Creators:
Jakob, Andrea1, Author
Becker, Johannes1, Author
Schöttli, Gertrud1, Author
Fritzsch, Günter2, Author           
Affiliations:
1Department of Biochemistry, Vesalianum, University of Basel, CH-4051 Basel, Switzerland, ou_persistent22              
2Department of Physical Chemistry, Max Planck Institute of Biophysics, Max Planck Society, ou_3264819              

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Free keywords: Mg2+; Perfusion; Adrenergic agonist, α1; (Rat liver)
 Abstract: The possibility that Mg2+ mobilization is stimulated in perfused liver by α1-adrenergic agonists was studied by measuring Mg2+ release in response to 0.5 and 20μM phenylephrine. During preperfusion exogenous Mg2+ was added to the medium to give 1.2 mM. 5 min before starting the addition of phenylephrine the infusion of exogenous Mg2+ was stopped. Mg2+ in the perfusate leaving the liver was measured by atomic absorption spectroscopy. Analysis of the Mg2+ decay curves with two exponential models indicated that phenylephrine caused dose-dependent Mg2+ release from perfused rat livers.

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Language(s): eng - English
 Dates: 1989-01-301989-03-27
 Publication Status: Issued
 Pages: 4
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1016/0014-5793(89)80267-4
 Degree: -

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Title: FEBS Letters
  Other : FEBS Lett.
Source Genre: Journal
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Publ. Info: Amsterdam : Elsevier
Pages: - Volume / Issue: 246 (1-2) Sequence Number: - Start / End Page: 127 - 130 Identifier: ISSN: 0014-5793
CoNE: https://pure.mpg.de/cone/journals/resource/954925399501