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  Reproducibility and Coverage of Human Whole-brain 1H FID MRSI at 9.4 T after Processing Pipeline Optimization

Ziegs, T., Wright, A., & Henning, A. (2021). Reproducibility and Coverage of Human Whole-brain 1H FID MRSI at 9.4 T after Processing Pipeline Optimization. Poster presented at 2021 ISMRM & SMRT Annual Meeting & Exhibition (ISMRM 2021).

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Ziegs, T1, 2, Author              
Wright, AM1, 2, Author              
Henning, A1, 2, Author              
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1Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_2528692              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              

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 Abstract: Whole-brain data were acquired using a non-accelerated, non-lipid-suppressed and ultra-short echo time 1H FID-MRSI 2D multi-slice sequence at 9.4 T on human subjects. Data was reconstructed, retrospectively lipid suppressed and fitted including a relaxation corrected macromolecular basis spectrum. Metabolite concentration maps showing expected concentration differences between gray and white matter could be achieved with 89-97% coverage of the whole brain for tCr, tCho, NAA, Glu, and mI. A stack of 32 mm thickness covering the central part of the cerebrum yields anatomically correct maps for Gln, Tau, GABA, NAAG, and GSH. The data acquisition and reconstruction lead to reproducible results.

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 Dates: 2021-05
 Publication Status: Published online
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Title: 2021 ISMRM & SMRT Annual Meeting & Exhibition (ISMRM 2021)
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Start-/End Date: 2021-05-15 - 2021-05-20

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Title: 2021 ISMRM & SMRT Annual Meeting & Exhibition (ISMRM 2021)
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 2005 Start / End Page: - Identifier: -