Deliz-Aguirre, R., Cao, F., Gerpott, F. H. U., Auevechanichkul, N., Chupanova, M., Mun, Y., et al. (2021). MyD88 oligomer size functions as a physical threshold to trigger IL1R Myddosome signaling. The Journal of Cell Biology: JCB, 220(7): e202012071. doi:10.1083/jcb.202012071.