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  Long-term stability of short-term intensive language–action therapy in chronic aphasia: A 1–2 year follow-up study

Doppelbauer, L., Mohr, B., Dreyer, F. R., Stahl, B., Büscher, V., & Pulvermüller, F. (2021). Long-term stability of short-term intensive language–action therapy in chronic aphasia: A 1–2 year follow-up study. Neurorehabilitation and Neural Repair, 35(10), 861-870. doi:10.1177/15459683211029235.

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Doppelbauer_2021.pdf (Verlagsversion), 893KB
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 Urheber:
Doppelbauer, Lea1, 2, 3, Autor
Mohr, Bettina4, 5, Autor
Dreyer, Felix R.1, 6, Autor
Stahl, Benjamin7, 8, 9, 10, Autor           
Büscher, Verena1, Autor
Pulvermüller, Friedemann1, 2, 3, 6, Autor
Affiliations:
1Brain Language Laboratory, Department of Philosophy and Humanities, FU Berlin, Germany, ou_persistent22              
2Einstein Center for Neurosciences Berlin (ECN), Germany, ou_persistent22              
3Berlin School of Mind and Brain, Humboldt University Berlin, Germany, ou_persistent22              
4Department Psychiatry, Charité University Medicine Berlin, Germany, ou_persistent22              
5Centre for Neuropsychology and Intensive Language Therapy (ZeNIS), Berlin, Germany, ou_persistent22              
6Cluster of Excellence Matters of Activity, Humboldt University Berlin, Germany, ou_persistent22              
7Department of Neurology, Charité University Medicine Berlin, Germany, ou_persistent22              
8Department of Neurology, Ernst Moritz Arndt University of Greifswald, Germany, ou_persistent22              
9Department Neurophysics (Weiskopf), MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_2205649              
10Psychologische Hochschule Berlin, Germany, ou_persistent22              

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Schlagwörter: Aphasia; Intensive language–action therapy; Rehabilitation; Speech therapy
 Zusammenfassung: Background. Intensive aphasia therapy can improve language functions in chronic aphasia over a short therapy interval of 2-4 weeks. For one intensive method, intensive language-action therapy, beneficial effects are well documented by a range of randomized controlled trials. However, it is unclear to date whether therapy-related improvements are maintained over years. Objective. The current study aimed at investigating long-term stability of ILAT treatment effects over circa 1-2 years (8-30 months). Methods. 38 patients with chronic aphasia participated in ILAT and were re-assessed at a follow-up assessment 8-30 months after treatment, which had been delivered 6-12.5 hours per week for 2-4 weeks. Results. A standardized clinical aphasia battery, the Aachen Aphasia Test, revealed significant improvements with ILAT that were maintained for up to 2.5 years. Improvements were relatively better preserved in comparatively young patients (<60 years). Measures of communicative efficacy confirmed improvements during intensive therapy but showed inconsistent long-term stability effects. Conclusions. The present data indicate that gains resulting from intensive speech-language therapy with ILAT are maintained up to 2.5 years after the end of treatment. We discuss this novel finding in light of a possible move from sparse to intensive therapy regimes in clinical practice.

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Sprache(n): eng - English
 Datum: 2021-07-072021-10
 Publikationsstatus: Erschienen
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 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: -
 Identifikatoren: DOI: 10.1177/15459683211029235
Anderer: epub 2021
PMID: 34232091
 Art des Abschluß: -

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Projektname : -
Grant ID : Pu 97/15-1 and 15-2, Mo 697/5-2
Förderprogramm : -
Förderorganisation : Deutsche Forschungsgemeinschaft
Projektname : -
Grant ID : ERC-2019-ADG 883811
Förderprogramm : -
Förderorganisation : European Research Council

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Titel: Neurorehabilitation and Neural Repair
Genre der Quelle: Zeitschrift
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Ort, Verlag, Ausgabe: Thousand Oaks, CA, USA : Sage
Seiten: - Band / Heft: 35 (10) Artikelnummer: - Start- / Endseite: 861 - 870 Identifikator: ISSN: 0888-4390
CoNE: https://pure.mpg.de/cone/journals/resource/0888-4390