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  Perspectives on ENCODE

The ENCODE Project Consortium, Snyder, M. P., Gingeras, T. R., Moore, J. E., Weng, Z., Gerstein, M. B., et al. (2020). Perspectives on ENCODE. Nature, 583, 693-698. doi:10.1038/s41586-020-2449-8.

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The ENCODE Project Consortium_2020.pdf (Publisher version), 2MB
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The ENCODE Project Consortium_2020.pdf
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© The Author(s) 2020

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 Creators:
The ENCODE Project Consortium, Author
Snyder, Michael P. , Author
Gingeras, Thomas R. , Author
Moore, Jill E., Author
Weng, Zhiping , Author
Gerstein, Mark B. , Author
Ren, Bing, Author
Hardison, Ross C. , Author
Stamatoyannopoulos, John A. , Author
Graveley, Brenton R. , Author
Feingold, Elise A. , Author
Pazin, Michael J. , Author
Pagan, Michael , Author
Gilchrist, Daniel A. , Author
Hitz, Benjamin C. , Author
Cherry, J. Michael , Author
Bernstein, Bradley E. , Author
Mendenhall, Eric M. , Author
Zerbino, Daniel R. , Author
Frankish, Adam , Author
Flicek, Paul , AuthorMyers , Richard M., AuthorMeissner, Alex1, 2, Author               more..
Affiliations:
1Dept. of Genome Regulation (Head: Alexander Meissner), Max Planck Institute for Molecular Genetics, Max Planck Society, ou_2379694              
2The ENCODE Project Consortium, ou_persistent22              

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 Abstract: The Encylopedia of DNA Elements (ENCODE) Project launched in 2003 with the long-term goal of developing a comprehensive map of functional elements in the human genome. These included genes, biochemical regions associated with gene regulation (for example, transcription factor binding sites, open chromatin, and histone marks) and transcript isoforms. The marks serve as sites for candidate cis-regulatory elements (cCREs) that may serve functional roles in regulating gene expression1. The project has been extended to model organisms, particularly the mouse. In the third phase of ENCODE, nearly a million and more than 300,000 cCRE annotations have been generated for human and mouse, respectively, and these have provided a valuable resource for the scientific community.

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Language(s): eng - English
 Dates: 2020-05-052020-07-292020-07-30
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1038/s41586-020-2449-8
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Title: Nature
  Abbreviation : Nature
Source Genre: Journal
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Publ. Info: London : Nature Publishing Group
Pages: 6 Volume / Issue: 583 Sequence Number: - Start / End Page: 693 - 698 Identifier: ISSN: 0028-0836 (print) 1476-4687 (online)
CoNE: https://pure.mpg.de/cone/journals/resource/954925427238