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  A novel paradigm for testing the initial coding of hierarchical relationships within the medial temporal lobe in a circuit specific manner

Scholz, R. (2020). A novel paradigm for testing the initial coding of hierarchical relationships within the medial temporal lobe in a circuit specific manner. Master Thesis, Humboldt University, Berlin.

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アイテムのパーマリンク: https://hdl.handle.net/21.11116/0000-0009-415D-6 版のパーマリンク: https://hdl.handle.net/21.11116/0000-000C-C460-A
資料種別: 学位論文

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200318 - masterarbeit_v025noa - final.pdf (ポストプリント), 902KB
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https://hdl.handle.net/21.11116/0000-0009-415F-4
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200318 - masterarbeit_v025noa - final.pdf
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Master Thesis
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Green
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公開
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application/pdf / [MD5]
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 作成者:
Scholz, Robert1, 2, 著者
Villringer, Arno1, 2, 3, 監修者           
Martins, Mauricio1, 2, 3, 4, 監修者           
所属:
1Berlin School of Mind and Brain, Humboldt Universität zu Berlin, Berlin, Germany, ou_persistent22              
2Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society, Leipzig, DE, ou_634549              
3Clinic for Cognitive Neurology, University Hospital Leipzig, Leipzig, Germany, ou_persistent22              
4Institut Jean Nicod, Département d’Etudes Cognitives, ENS, EHESS, CNRS, PSL Research University, Paris, France, ou_persistent22              

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 要旨: The Medial Temporal Lobe (MTL) is central to spatial navigation and to the processing of conceptual associations, functions which can be implemented via the grid cell system. Evidence exists that also hierarchical processing - an integral part of cognitive capacities such as language, motor action and sequential planning - draws on the MTL. This raises the question of whether hierarchical processing shares the same cellular substrate with spatial navigation and concept association formation. Here we present two novel tasks (hierarchy and control) specifically designed to test (using fMRI) whether grid cells also support the representation of hierarchical relations. We present the first results of their behavioral validation with respect to specificity, and show that our hierarchical task, but not the control task, correlates well with other tasks that necessitate hierarchical processing (Tower of Hanoi and a Visual Recursion Task). Furthermore, we show that some of these effects remain even when removing the shared variance that can be explained by a range of unspecific factors. This gives reason to believe that our task is a valid method for probing the relationship between grid cells and hierarchical processing.

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 日付: 2020-042020-042021-092020-04
 出版の状態: 出版
 ページ: -
 出版情報: Berlin : Humboldt University
 目次: -
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 識別子(DOI, ISBNなど): -
 学位: 修士号 (Master)

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