Computational modeling and experimental validation of the EPI-X4/CXCR4 complex 
allows rational design of small peptide antagonists

Sokkar, Pandian; Harms, Mirja; Stürzel, Christina; Gilg, Andrea; Kizilsavas, Gönül; Raasholm, Martina; Preising, Nico; Wagner, Manfred; Kirchhoff, Frank; Ständker, Ludger; Weidinger, Gilbert; Mayer, Benjamin; Münch, Jan; Sanchez-Garcia, Elsa

doi:10.1038/s42003-021-02638-5

Local TagsRelease HistoryDetailsSummary

Computational modeling and experimental validation of the EPI-X4/CXCR4 complex allows rational design of small peptide antagonists

Sokkar, P., Harms, M., Stürzel, C., Gilg, A., Kizilsavas, G., Raasholm, M., et al. (2021). Computational modeling and experimental validation of the EPI-X4/CXCR4 complex allows rational design of small peptide antagonists. Communications Biology, 4(1): 1113. doi:10.1038/s42003-021-02638-5.

Item is Released

show all hide all

Basic

show hide

Item Permalink: https://hdl.handle.net/21.11116/0000-0009-50B3-2 Version Permalink: https://hdl.handle.net/21.11116/0000-0009-50B4-1

Genre: Journal Article

Files

show Files

hide Files

:

s42003-021-02638-5.pdf (Publisher version), 5MB

View Save

File Permalink:
https://hdl.handle.net/21.11116/0000-0009-50B5-0

Name:
s42003-021-02638-5.pdf

Description:
-

OA-Status:

Visibility:
Public

MIME-Type / Checksum:
application/pdf / [MD5]

Technical Metadata:

View

Copyright Date:
2021

Copyright Info:
The Author(s)

License:
https://creativecommons.org/licenses/by/4.0/

Locators

show

Creators

show

hide

Creators:
Sokkar, Pandian^{1, 2}, Author
Harms, Mirja³, Author
Stürzel, Christina³, Author
Gilg, Andrea³, Author
Kizilsavas, Gönül⁴, Author
Raasholm, Martina⁵, Author
Preising, Nico⁶, Author
Wagner, Manfred⁴, Author
Kirchhoff, Frank³, Author
Ständker, Ludger⁶, Author
Weidinger, Gilbert⁵, Author
Mayer, Benjamin⁷, Author
Münch, Jan^{3, 6}, Author
Sanchez-Garcia, Elsa¹, Author

Affiliations:
1Computational Biochemistry, Center of Medical Biotechnology, University of Duisburg-Essen, Essen, Germany, ou_persistent22
2Faculty of Allied Health Sciences, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam, Tamil Nadu, India, ou_persistent22
3Institute of Molecular Virology, Ulm University Medical Center, Ulm, Germany, ou_persistent22
4Dept. Weil: Synthesis of Macromolecules, MPI for Polymer Research, Max Planck Society, ou_2301691
5Institute of Biochemistry and Molecular Biology, Ulm University, Ulm, Germany, ou_persistent22
6Core Facility Functional Peptidomics, Ulm University Medical Center, Ulm, Germany, ou_persistent22
7Institute for Epidemiology and Medical Biometry, Ulm University, Ulm, Germany, ou_persistent22

Content

show

Details

show

hide

Language(s): eng - English

Dates: Published Online: 2021-09-22

Publication Status: Published online

Pages: -

Publishing info: -

Table of Contents: -

Rev. Type: -

Identifiers: DOI: 10.1038/s42003-021-02638-5

Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show

hide

Title: Communications Biology

Source Genre: Journal

Creator(s):

Affiliations:

Publ. Info: London : Springer Nature

Pages: - Volume / Issue: 4 (1) Sequence Number: 1113 Start / End Page: - Identifier: ISSN: 2399-3642
CoNE: https://pure.mpg.de/cone/journals/resource/2399-3642