English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Quantitative Susceptibility Mapping of the Basal Ganglia and Thalamus at 9.4 Tesla

Kumar, V., Scheffler, K., Hagberg, G., & Grodd, W. (2021). Quantitative Susceptibility Mapping of the Basal Ganglia and Thalamus at 9.4 Tesla. Frontiers in Neuroanatomy, 15: 725731, pp. 1-12. doi:10.3389/fnana.2021.725731.

Item is

Basic

show hide
Genre: Journal Article

Files

show Files

Locators

show
hide
Description:
-

Creators

show
hide
 Creators:
Kumar, VJ1, 2, Author              
Scheffler, K1, 2, Author              
Hagberg, GE1, 2, Author              
Grodd, W1, 2, Author              
Affiliations:
1Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              

Content

show
hide
Free keywords: -
 Abstract: The thalamus (Th) and basal ganglia (BG) are central subcortical connectivity hubs of the human brain, whose functional anatomy is still under intense investigation. Nevertheless, both substructures contain a robust and reproducible functional anatomy. The quantitative susceptibility mapping (QSM) at ultra-high field may facilitate an improved characterization of the underlying functional anatomy in vivo. We acquired high-resolution QSM data at 9.4 Tesla in 21 subjects, and analyzed the thalamic and BG by using a prior defined functional parcellation. We found a more substantial contribution of paramagnetic susceptibility sources such as iron in the pallidum in contrast to the caudate, putamen, and Th in descending order. The diamagnetic susceptibility sources such as myelin and calcium revealed significant contributions in the Th parcels compared with the BG. This study presents a detailed nuclei-specific delineation of QSM-provided diamagnetic and paramagnetic susceptibility sources pronounced in the BG and the Th. We also found a reasonable interindividual variability as well as slight hemispheric differences. The results presented here contribute to the microstructural knowledge of the Th and the BG. In specific, the study illustrates QSM values (myelin, calcium, and iron) in functionally similar subregions of the Th and the BG.

Details

show
hide
Language(s):
 Dates: 2021-09
 Publication Status: Published online
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.3389/fnana.2021.725731
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Frontiers in Neuroanatomy
  Abbreviation : Front Neuroanat
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Lausanne, Switzerland : Frontiers Research Foundation
Pages: - Volume / Issue: 15 Sequence Number: 725731 Start / End Page: 1 - 12 Identifier: ISSN: 1662-5129
CoNE: https://pure.mpg.de/cone/journals/resource/1662-5129