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  Slow update of internal representations impedes synchronization in autism

Vishne, G., Jacoby, N., Malinovitch, T., Epstein, T., Frenkel, O., & Ahissar, M. (2021). Slow update of internal representations impedes synchronization in autism. Nature Communications, 12: 5439. doi:10.1038/s41467-021-25740-y.

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21-cap-jac-02-slow.pdf (Verlagsversion), 2MB
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Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder

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 Urheber:
Vishne, Gal1, Autor
Jacoby, Nori2, Autor           
Malinovitch, Tamar3, Autor
Epstein, Tamir4, Autor
Frenkel, Or5, Autor
Ahissar, Merav1, 5, Autor
Affiliations:
1Edmond and Lily Safra Center for Brain Sciences, Hebrew University, Jerusalem, Israel, ou_persistent22              
2Research Group Computational Auditory Perception, Max Planck Institute for Empirical Aesthetics, Max Planck Society, ou_3024247              
3Cognitive Science Department, Hebrew University, Jerusalem, Israel, ou_persistent22              
4Psychiatric Division, Sheba Medical Center, Tel-Hashomer, Israel, ou_persistent22              
5Psychology Department, Hebrew University , Jerusalem, Israel, ou_persistent22              

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Schlagwörter: Autism spectrum disorders, Computational neuroscience, Human behaviour
 Zusammenfassung: Autism is a neurodevelopmental disorder characterized by impaired social skills, motor and perceptual atypicalities. These difficulties were explained within the Bayesian framework as either reflecting oversensitivity to prediction errors or – just the opposite – slow updating of such errors. To test these opposing theories, we administer paced finger-tapping, a synchronization task that requires use of recent sensory information for fast error-correction. We use computational modelling to disentangle the contributions of error-correction from that of noise in keeping temporal intervals, and in executing motor responses. To assess the specificity of tapping characteristics to autism, we compare performance to both neurotypical individuals and individuals with dyslexia. Only the autism group shows poor sensorimotor synchronization. Trial-by-trial modelling reveals typical noise levels in interval representations and motor responses. However, rate of error correction is reduced in autism, impeding synchronization ability. These results provide evidence for slow updating of internal representations in autism.

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Sprache(n): eng - English
 Datum: 2020-10-122021-08-182021-09-14
 Publikationsstatus: Online veröffentlicht
 Seiten: -
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: Expertenbegutachtung
 Identifikatoren: DOI: 10.1038/s41467-021-25740-y
 Art des Abschluß: -

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Titel: Nature Communications
  Kurztitel : Nat. Commun.
Genre der Quelle: Zeitschrift
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Affiliations:
Ort, Verlag, Ausgabe: London : Nature Publishing Group
Seiten: - Band / Heft: 12 Artikelnummer: 5439 Start- / Endseite: - Identifikator: ISSN: 2041-1723
CoNE: https://pure.mpg.de/cone/journals/resource/2041-1723