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  USP28 deletion and small-molecule inhibition destabilizes c-MYC and elicits regression of squamous cell lung carcinoma

Ruiz, E. J., Pinto-Fernandez, A., Turnball, A. P., Lan, L., Charlton, T. M., Scott, H. C., et al. (2021). USP28 deletion and small-molecule inhibition destabilizes c-MYC and elicits regression of squamous cell lung carcinoma. eLife, 10:e71596, pp. 1-23. doi:10.7554/eLife.71596.

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 Creators:
Ruiz, E Josue1, Author
Pinto-Fernandez, Adan 1, Author
Turnball, Andrew P.1, Author
Lan, Linxiang1, Author
Charlton, Thomas M. 1, Author
Scott, Hannah C.1, Author
Damianou, Andreas1, Author
Vere, George1, Author
Riising, Eva M.1, Author
Da Costa, Clive1, Author
Krajewski, Wojciech W.1, Author
Guerin, David1, Author
Kearns, Jeffrey D.1, Author
Ioannidis , Stephanos1, Author
Katz, Marie1, Author
McKinnon, Crystal1, Author
O´Connell, Jonathan1, Author
Moncaut, Natalia1, Author
Rosewell, Ian1, Author
Nye, Emma1, Author
Jones, Neil1, AuthorHeride, Claire1, AuthorGersch, Malte2, Author           Wu, Min1, AuthorDinsmore, Christopher J. 1, AuthorHammonds, Tim R.1, AuthorKim, Sunkyu1, AuthorKomander, David1, AuthorUrbe, Sylvie1, AuthorClague, Michael J.1, AuthorKessler, Benedikt M.1, AuthorBehrens, Axel1, Author more..
Affiliations:
1External Organizations, ou_persistent22              
2Chemical Genomics Center of the MPS, Max Planck Institute of Molecular Physiology, Max Planck Society, ou_1753292              

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Free keywords: USP28; biochemistry; c-MYC; cancer biology; chemical biology; human; squamous cell lung cancer
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Language(s): eng - English
 Dates: 2021-10-12
 Publication Status: Issued
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.7554/eLife.71596
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Title: eLife
Source Genre: Journal
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Publ. Info: Cambridge : eLife Sciences Publications
Pages: - Volume / Issue: - Sequence Number: 10:e71596 Start / End Page: 1 - 23 Identifier: ISSN: 2050-084X
CoNE: https://pure.mpg.de/cone/journals/resource/2050-084X