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  A checklist for assessing the methodological quality of concurrent tES-fMRI studies (ContES checklist): A consensus study and statement

Ekhtiari, H., Ghobadi-Azbari, P., Thielscher, A., Antal, A., Li, L. M., Shereen, A. D., et al. (2022). A checklist for assessing the methodological quality of concurrent tES-fMRI studies (ContES checklist): A consensus study and statement. Nature Protocols, 17(3), 596-617. doi:10.1038/s41596-021-00664-5.

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Ekhtiari, Hamed, Author
Ghobadi-Azbari, Peyman, Author
Thielscher, Axel, Author
Antal, Andrea, Author
Li, Lucia M., Author
Shereen, A. Duke, Author
Cabral-Calderin, Yuranny, Author
Keeser, Daniel, Author
Bergmann, Til Ole, Author
Jamil, Asif, Author
Violante, Ines R., Author
Almeida, Jorge, Author
Meinzer, Marcus, Author
Siebner, Hartwig R., Author
Woods, Adam J., Author
Stagg, Charlotte J., Author
Abend, Rany, Author
Antonenko, Daria, Author
Auer, Tibor, Author
Bächinger, Marc, Author
Baeken, Chris, AuthorBarron, Helen C., AuthorChase, Henry W., AuthorCrinion, Jenny, AuthorDatta, Abhishek, AuthorDavis, Matthew H., AuthorEbrahimi, Mohsen, AuthorEsmaeilpour, Zeinab, AuthorFalcone, Brian, AuthorFiori, Valentina, AuthorGhodratitoostani, Iman, AuthorGilam, Gadi, AuthorGrabner, Roland H., AuthorGreenspan, Joel D., AuthorGroen, Georg, AuthorHartwigsen, Gesa1, Author                 Hauser, Tobias U., AuthorHerrmann, Christoph S., AuthorJuan, Chi-Hung, AuthorKrekelberg, Bart, AuthorLefebvre, Stephanie, AuthorLiew, Sook-Lei, AuthorMadsen, Kristoffer H., AuthorMahdavifar-Khayati, Rasoul, AuthorMalmir, Nastaran, AuthorMarangolo, Paola, AuthorMartin, Andrew K., AuthorMeeker, Timothy J., AuthorArdabili, Hossein Mohaddes, AuthorMoisa, Marius, AuthorMomi, Davide, AuthorMulyana, Beni, AuthorOpitz, Alexander, AuthorOrlov, Natasza, AuthorRagert, Patrick2, Author           Ruff, Christian C., AuthorRuffini, Giulio, AuthorRuttorf, Michaela, AuthorSangchooli, Arshiya, AuthorSchellhorn, Klaus, AuthorSchlaug, Gottfried, AuthorSehm, Bernhard2, Author                 Soleimani, Ghazaleh, AuthorTavakoli, Hosna, AuthorThompson, Benjamin, AuthorTimmann, Dagmar, AuthorTsuchiyagaito, Aki, AuthorUlrich, Martin, AuthorVosskuhl, Johannes, AuthorWeinrich, Christiane A., AuthorZare-Bidoky, Mehran, AuthorZhang, Xiaochu, AuthorZoefel, Benedikt, AuthorNitsche, Michael A., AuthorBikson, Marom, Author more..
1Lise Meitner Research Group Cognition and Plasticity, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_3025665              
2Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634549              


Free keywords: Cognitive neuroscience; Neuroscience
 Abstract: Low-intensity transcranial electrical stimulation (tES), including alternating or direct current stimulation, applies weak electrical stimulation to modulate the activity of brain circuits. Integration of tES with concurrent functional MRI (fMRI) allows for the mapping of neural activity during neuromodulation, supporting causal studies of both brain function and tES effects. Methodological aspects of tES-fMRI studies underpin the results, and reporting them in appropriate detail is required for reproducibility and interpretability. Despite the growing number of published reports, there are no consensus-based checklists for disclosing methodological details of concurrent tES-fMRI studies. The objective of this work was to develop a consensus-based checklist of reporting standards for concurrent tES-fMRI studies to support methodological rigor, transparency and reproducibility (ContES checklist). A two-phase Delphi consensus process was conducted by a steering committee (SC) of 13 members and 49 expert panelists through the International Network of the tES-fMRI Consortium. The process began with a circulation of a preliminary checklist of essential items and additional recommendations, developed by the SC on the basis of a systematic review of 57 concurrent tES-fMRI studies. Contributors were then invited to suggest revisions or additions to the initial checklist. After the revision phase, contributors rated the importance of the 17 essential items and 42 additional recommendations in the final checklist. The state of methodological transparency within the 57 reviewed concurrent tES-fMRI studies was then assessed by using the checklist. Experts refined the checklist through the revision and rating phases, leading to a checklist with three categories of essential items and additional recommendations: (i) technological factors, (ii) safety and noise tests and (iii) methodological factors. The level of reporting of checklist items varied among the 57 concurrent tES-fMRI papers, ranging from 24% to 76%. On average, 53% of checklist items were reported in a given article. In conclusion, use of the ContES checklist is expected to enhance the methodological reporting quality of future concurrent tES-fMRI studies and increase methodological transparency and reproducibility.


Language(s): eng - English
 Dates: 2020-12-292021-11-122022-02-042022-03
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1038/s41596-021-00664-5
Other: epub 2022
PMID: 35121855
 Degree: -



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Title: Nature Protocols
  Other : Nat. Protoc.
Source Genre: Journal
Publ. Info: London, UK : Nature Publishing Group
Pages: - Volume / Issue: 17 (3) Sequence Number: - Start / End Page: 596 - 617 Identifier: ISSN: 1750-2799
CoNE: https://pure.mpg.de/cone/journals/resource/1000000000223800_1