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  Objective comparison of methods to decode anomalous diffusion

Munoz-Gil, G., Volpe, G., Garcia-March, M. A., Aghion, E., Argun, A., Hong, C. B., et al. (2021). Objective comparison of methods to decode anomalous diffusion. Nature Communications, 12(1): 6253. doi:10.1038/s41467-021-26320-w.

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 Creators:
Munoz-Gil, Gorka1, Author
Volpe, Giovanni1, Author
Garcia-March, Miguel Angel1, Author
Aghion, Erez2, Author           
Argun, Aykut1, Author
Hong, Chang Beom1, Author
Bland, Tom1, Author
Bo, Stefano2, Author           
Conejero, J. Alberto1, Author
Firbas, Nicolas1, Author
Orts, Oscar1, Author
Gentili, Alessia1, Author
Huang, Zihan1, Author
Jeon, Jae-Hyung1, Author
Kabbech, Helene1, Author
Kim, Yeongjin1, Author
Kowalek, Patrycja1, Author
Krapf, Diego1, Author
Loch-Olszewska, Hanna1, Author
Lomholt, Michael A.1, Author
Masson, Jean-Baptiste1, AuthorMeyer, Philipp G.2, Author           Park, Seongyu1, AuthorRequena, Borja1, AuthorSmal, Ihor1, AuthorSong, Taegeun1, AuthorSzwabinski, Janusz1, AuthorThapa, Samudrajit1, AuthorVerdier, Hippolyte1, AuthorVolpe, Giorgio1, AuthorWidera, Artur1, AuthorLewenstein, Maciej1, AuthorMetzler, Ralf1, AuthorManzo, Carlo1, Author more..
Affiliations:
1external, ou_persistent22              
2Max Planck Institute for the Physics of Complex Systems, Max Planck Society, ou_2117288              

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 MPIPKS: Stochastic processes
 Abstract: Deviations from Brownian motion leading to anomalous diffusion are found in transport dynamics from quantum physics to life sciences. The characterization of anomalous diffusion from the measurement of an individual trajectory is a challenging task, which traditionally relies on calculating the trajectory mean squared displacement. However, this approach breaks down for cases of practical interest, e.g., short or noisy trajectories, heterogeneous behaviour, or non-ergodic processes. Recently, several new approaches have been proposed, mostly building on the ongoing machine-learning revolution. To perform an objective comparison of methods, we gathered the community and organized an open competition, the Anomalous Diffusion challenge (AnDi). Participating teams applied their algorithms to a commonly-defined dataset including diverse conditions. Although no single method performed best across all scenarios, machine-learning-based approaches achieved superior performance for all tasks. The discussion of the challenge results provides practical advice for users and a benchmark for developers.
Deviations from Brownian motion leading to anomalous diffusion are ubiquitously found in transport dynamics but often difficult to characterize. Here the authors compare approaches for single trajectory analysis through an open competition, showing that machine learning methods outperform classical approaches.

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 Dates: 2021-10-292021-10-29
 Publication Status: Issued
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 Identifiers: ISI: 000712910500024
DOI: 10.1038/s41467-021-26320-w
arXiv: 2105.06766
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Title: Nature Communications
  Abbreviation : Nat. Commun.
Source Genre: Journal
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Publ. Info: London : Nature Publishing Group
Pages: - Volume / Issue: 12 (1) Sequence Number: 6253 Start / End Page: - Identifier: ISSN: 2041-1723
CoNE: https://pure.mpg.de/cone/journals/resource/2041-1723