English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Double- to Single-Strand Transition Induces Forces and Motion in DNA Origami Nanostructures

Gur, F. N., Kempter, S., Schueder, F., Sikeler, C., Urban, M. J., Jungmann, R., et al. (2021). Double- to Single-Strand Transition Induces Forces and Motion in DNA Origami Nanostructures. Advanced Materials, 33(37): 2101986. doi:10.1002/adma.202101986.

Item is

Files

show Files
hide Files
:
Advanced Materials - 2021 - G r - Double‐ to Single‐Strand Transition Induces Forces and Motion in DNA Origami.pdf (Publisher version), 2MB
Name:
Advanced Materials - 2021 - G r - Double‐ to Single‐Strand Transition Induces Forces and Motion in DNA Origami.pdf
Description:
-
OA-Status:
Visibility:
Public
MIME-Type / Checksum:
application/pdf / [MD5]
Technical Metadata:
Copyright Date:
-
Copyright Info:
© 2021 The Authors. Open access funding enabled and organized by Projekt DEAL.

Locators

show

Creators

show
hide
 Creators:
Gur, Fatih N.1, Author
Kempter, Susanne1, Author
Schueder, Florian2, Author           
Sikeler, Christoph1, Author
Urban, Maximilian J.1, Author
Jungmann, Ralf2, Author           
Nickels, Philipp C.1, Author
Liedl, Tim1, Author
Affiliations:
1external, ou_persistent22              
2Jungmann, Ralf / Molecular Imaging and Bionanotechnology, Max Planck Institute of Biochemistry, Max Planck Society, ou_2149679              

Content

show
hide
Free keywords: SUPERRESOLUTION MICROSCOPY; FOLDING DNA; NANOROBOT; DEVICES; SHAPES; GOLDChemistry; Science & Technology - Other Topics; Materials Science; Physics; DNA origami nanostructures; DNA-PAINT; entropic force; nanoparticles; single-stranded DNA; super-resolution microscopy;
 Abstract: The design of dynamic, reconfigurable devices is crucial for the bottom-up construction of artificial biological systems. DNA can be used as an engineering material for the de-novo design of such dynamic devices. A self-assembled DNA origami switch is presented that uses the transition from double- to single-stranded DNA and vice versa to create and annihilate an entropic force that drives a reversible conformational change inside the switch. It is distinctively demonstrated that a DNA single-strand that is extended with 0.34 nm per nucleotide - the extension this very strand has in the double-stranded configuration - exerts a contractive force on its ends leading to large-scale motion. The operation of this type of switch is demonstrated via transmission electron microscopy, DNA-PAINT super-resolution microscopy and darkfield microscopy. The work illustrates the intricate and sometimes counter-intuitive forces that act in nanoscale physical systems that operate in fluids.

Details

show
hide
Language(s): eng - English
 Dates: 2021-09-16
 Publication Status: Published online
 Pages: 6
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: ISI: 000679851800001
DOI: 10.1002/adma.202101986
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Advanced Materials
  Other : Adv. Mater.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Weinheim : Wiley-VCH
Pages: - Volume / Issue: 33 (37) Sequence Number: 2101986 Start / End Page: - Identifier: ISSN: 0935-9648
CoNE: https://pure.mpg.de/cone/journals/resource/954925570855