English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
 
 
DownloadE-Mail
  Multiplexed computations in retinal ganglion cells of a single type

Deny, S., Ferrari, U., Macé, E., Yger, P., Caplette, R., Picaud, S., et al. (2017). Multiplexed computations in retinal ganglion cells of a single type. Nature Communications, 8: 1964. doi:10.1038/s41467-017-02159-y.

Item is

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Deny, S., Author
Ferrari, U., Author
Macé, Emilie1, Author           
Yger, P., Author
Caplette, R., Author
Picaud, S., Author
Tkacik, G., Author
Marre, O., Author
Affiliations:
1Universite Paris VII, France, ou_persistent22              

Content

show
hide
Free keywords: nonlinear spatial summation receptive-fields bipolar cells synaptic-transmission functional circuitry remote stimulation mammalian retina amacrine cell rat retina responses Science & Technology - Other Topics
 Abstract: In the early visual system, cells of the same type perform the same computation in different places of the visual field. How these cells code together a complex visual scene is unclear. A common assumption is that cells of a single-type extract a single-stimulus feature to form a feature map, but this has rarely been observed directly. Using large-scale recordings in the rat retina, we show that a homogeneous population of fast OFF ganglion cells simultaneously encodes two radically different features of a visual scene. Cells close to a moving object code quasilinearly for its position, while distant cells remain largely invariant to the object's position and, instead, respond nonlinearly to changes in the object's speed. We develop a quantitative model that accounts for this effect and identify a disinhibitory circuit that mediates it. Ganglion cells of a single type thus do not code for one, but two features simultaneously. This richer, flexible neural map might also be present in other sensory systems.

Details

show
hide
Language(s): eng - English
 Dates: 2017
 Publication Status: Issued
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: Other: WOS:000417241200004
DOI: 10.1038/s41467-017-02159-y
ISSN: 2041-1723
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Nature Communications
  Abbreviation : Nat. Commun.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: London : Nature Publishing Group
Pages: - Volume / Issue: 8 Sequence Number: 1964 Start / End Page: - Identifier: ISSN: 2041-1723
CoNE: https://pure.mpg.de/cone/journals/resource/2041-1723