English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Glucose activation of adenylate cyclase in Saccharomyces cerevisiae mutants lacking glucose-phosphorylating enzymes

Pardo, L. A., Lazo, P. S., & Ramos, S. (1993). Glucose activation of adenylate cyclase in Saccharomyces cerevisiae mutants lacking glucose-phosphorylating enzymes. Cellular Signalling, 5(4), 435-441. doi:10.1016/0898-6568(93)90083-x.

Item is

Basic

show hide
Genre: Journal Article

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Pardo, L. A.1, Author           
Lazo, P. S., Author
Ramos, S., Author
Affiliations:
1Oncophysiology, Max Planck Institute of Experimental Medicine, Max Planck Society, ou_2559695              

Content

show
hide
Free keywords: -
 Abstract: The "in vitro" activation by glucose of the RAS-adenylate cyclase system in membranes from a strain of Saccharomyces cerevisiae lacking any functional glucose kinase activity presents similar features to those of the wild type. However, this triple mutant appears to be unable to produce the glucose-induced increase of cAMP levels "in vivo". The results obtained in vitro indicate that the signal transduction mechanism is active in the mutant cells and suggest that the absence of intracellular acidification in vivo might be responsible for the lack of response to glucose.

Details

show
hide
Language(s):
 Dates: 1993-07
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1016/0898-6568(93)90083-x
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Cellular Signalling
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: 5 (4) Sequence Number: - Start / End Page: 435 - 441 Identifier: -