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  Real-time quantification of T(2)(*) changes using multiecho planar imaging and numerical methods

Hagberg, G., Indovina, I., Sanes, J., & Posse, S. (2002). Real-time quantification of T(2)(*) changes using multiecho planar imaging and numerical methods. Magnetic Resonance in Medicine, 48(5), 877-882. doi:10.1002/mrm.10283.

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 Creators:
Hagberg, GE1, Author              
Indovina, I, Author
Sanes, JN, Author
Posse, S, Author
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1External Organizations, ou_persistent22              

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 Abstract: Conventional approaches to quantify whole brain Turn:x-wiley:07403194:media:MRM10283:tex2gif-stack-3 maps use nonlinear regression with intensive computational requirements that therefore likely limit quantitative Turn:x-wiley:07403194:media:MRM10283:tex2gif-stack-4 mapping for real-time applications. To overcome these limitations an alternative method, NumARTurn:x-wiley:07403194:media:MRM10283:tex2gif-stack-5 (NUMerical Algorithm for Real-time Turn:x-wiley:07403194:media:MRM10283:tex2gif-stack-6 mapping) that directly calculates Turn:x-wiley:07403194:media:MRM10283:tex2gif-stack-7 by a linear combination of images obtained at three or more different echo times was developed. NumARTurn:x-wiley:07403194:media:MRM10283:tex2gif-stack-8, linear least-squares, and nonlinear regression techniques were applied to multiecho planar images of the human brain and to simulated data. Although NumARTurn:x-wiley:07403194:media:MRM10283:tex2gif-stack-9 may overestimate Turn:x-wiley:07403194:media:MRM10283:tex2gif-stack-10, it yields comparable values to regression techniques in cortical and subcortical areas, with only moderate deviations for echo spacings between 18 and 40 ms. NumARTurn:x-wiley:07403194:media:MRM10283:tex2gif-stack-11, like linear regression, requires 2% of the computational time needed for nonlinear regression and compares favorably with linear regression due to its higher precision. The use of NumARTurn:x-wiley:07403194:media:MRM10283:tex2gif-stack-12 for continuous on-line Turn:x-wiley:07403194:media:MRM10283:tex2gif-stack-13 mapping in real time fMRI studies is shown.

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 Dates: 2002-11
 Publication Status: Published in print
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 Rev. Type: -
 Identifiers: DOI: 10.1002/mrm.10283
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Title: Magnetic Resonance in Medicine
Source Genre: Journal
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Publ. Info: New York : Wiley-Liss
Pages: - Volume / Issue: 48 (5) Sequence Number: - Start / End Page: 877 - 882 Identifier: ISSN: 0740-3194
CoNE: https://pure.mpg.de/cone/journals/resource/954925538149