English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
 
 
DownloadE-Mail
  Hidden protein functions and what they may teach us

Schwille, P., & Frohn, B. P. (2022). Hidden protein functions and what they may teach us. Trends in Cell Biology, 32(2), 102-109. doi:10.1016/j.tcb.2021.09.006.

Item is

Basic

show hide
Genre: Journal Article
Subtitle : Opinion

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Schwille, Petra1, Author              
Frohn, Bela P.1, Author
Affiliations:
1Schwille, Petra / Cellular and Molecular Biophysics, Max Planck Institute of Biochemistry, Max Planck Society, ou_1565169              

Content

show
hide
Free keywords: SYNTHETIC BIOLOGY; PHASE-SEPARATION; FTSZ FILAMENTS; RECONSTITUTION; IGEMCell Biology;
 Abstract: Bottom-up synthetic biology is a new research field with the goal of constructing living systems from a minimal number of functional components. The key challenges are, first, to identify a necessary canon of functions for a system to be considered alive, and second, to reconstitute these respective modules in vitro. When using proteins as obvious candidates, it appears that not only some of their described physiological functions fail to unfold outside the cellular context, but that completely new and unexpected functions are being observed. We put these insights in the context of other recent findings on protein functionality and discuss their potential role in the emergence and evolution of life.

Details

show
hide
Language(s): eng - English
 Dates: 2022
 Publication Status: Published in print
 Pages: 8
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: ISI: 000752561000004
DOI: 10.1016/j.tcb.2021.09.006
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Trends in Cell Biology
  Other : Trends Cell Biol.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Cambridge, UK : Elsevier Current Trends
Pages: - Volume / Issue: 32 (2) Sequence Number: - Start / End Page: 102 - 109 Identifier: ISSN: 0962-8924
CoNE: https://pure.mpg.de/cone/journals/resource/954925580131