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Schlagwörter:
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Zusammenfassung:
The primary structure of the ceramide tetracontasaccharide (1) from rabbit erythrocyte
membranes has been determined with the aid of 600-MHz two-dimensional phase-sensitive correlated, “totally
correlated” (TOCSY, homonuclear Hartmann-Hahn), relayed coherence transfer, triple quantum filtered,
and nuclear Overhauser enhancement NMR spectra. It was shown that obtaining subspectra of the
constituent sugar residues from a totally correlated spectrum and assigning the resonances occurring in these
subspectra by analyzing the relevant cross-peaks in phase-sensitive correlated spectra is the most efficient
way for establishing complex oligosaccharide structures. This analysis has shown 1 to be the highest
homologue of the multiantennary neolactoglycosphingolipids of the following general formula with = 7:
Galo,1-3Gal01- 4GlcNAc01-3Gal/31
6
Gala1-3Gal/31-4GlcNAC/3
