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  Identifying modulation of brain states by optogenetic stimulation of lateral hypothalamus

Takahashi, K., Chen, Y., Pais, P., & Yu, X. (2022). Identifying modulation of brain states by optogenetic stimulation of lateral hypothalamus. Poster presented at Joint Annual Meeting ISMRM-ESMRMB & ISMRT 31st Annual Meeting (ISMRM 2022), London, UK.

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 Creators:
Takahashi, K1, Author              
Chen, Y1, Author              
Pais, P, Author              
Yu, X, Author              
Affiliations:
1Research Group Translational Neuroimaging and Neural Control, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_2528695              

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 Abstract: The lateral hypothalamus (LH) plays an important role in regulating the brain state changes during sleep and arousal state fluctuation. Although the anatomical projections of LH have been well-investigated, the brain-wide functional map by LH stimulation under different brain states has not been characterized. Here, we applied fMRI to characterize the whole brain activation maps under different brain states during anesthesia in response to LH optogenetic stimulation. We demonstrate that the underlying brain state determines distinct functional mapping features upon LH activation.

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 Dates: 2022-05
 Publication Status: Published online
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Title: Joint Annual Meeting ISMRM-ESMRMB & ISMRT 31st Annual Meeting (ISMRM 2022)
Place of Event: London, UK
Start-/End Date: 2022-05-07 - 2022-05-12

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Title: Joint Annual Meeting ISMRM-ESMRMB & ISMRT 31st Annual Meeting (ISMRM 2022)
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 1824 Start / End Page: - Identifier: -