hide
Free keywords:
-
Abstract:
The tracing of glucose metabolism is of interest in many pathologies of the human brain. In this abstract, we compare the information content of 2H MRSI detected deuterium metabolic imaging (DMI) to quantitative exchanged-labeled turnover 1H MRS (QELT), both measured at B0 = 9.4 Tesla. An uptake of 2H labeling was detectable for different metabolites for both methods. Consistent changes in 2H labeled Glx after the oral administration of [6,6’-2H2]-glucose were detected in the brain of healthy human subjects.
