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  Proposal of a population wide genome-based testing for Covid-19

Lehrach, H., Curtis, J., Lange, B., Ogilvie, L. A., Gauss, R., Steininger, C., et al. (2022). Proposal of a population wide genome-based testing for Covid-19. Scientific Reports, 12: 5618. doi:10.1038/s41598-022-08934-2.

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ScientificRep_Lehrach et al_2022.pdf (Publisher version), 2MB
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 Creators:
Lehrach, Hans1, 2, Author              
Curtis, Jon, Author
Lange, Bodo, Author
Ogilvie, Lesley A., Author
Gauss, Richard , Author
Steininger, Christoph , Author
Scholz, Erhard , Author
Kreck, Matthias , Author
Affiliations:
1Emeritus Group of Vertebrate Genomics (Head: Hans Lehrach), Max Planck Institute for Molecular Genetics, Max Planck Society, ou_2385697              
2Alacris Theranostics GmbH, Berlin, Germany, ou_persistent22              

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 Abstract: Our lives (and deaths) have by now been dominated for two years by COVID-19, a pandemic that has caused hundreds of millions of disease cases, millions of deaths, trillions in economic costs, and major restrictions on our freedom. Here we suggest a novel tool for controlling the COVID-19 pandemic. The key element is a method for a population-scale PCR-based testing, applied on a systematic and repeated basis. For this we have developed a low cost, highly sensitive virus-genome-based test. Using Germany as an example, we demonstrate by using a mathematical model, how useful this strategy could have been in controlling the pandemic. We show using real-world examples how this might be implemented on a mass scale and discuss the feasibility of this approach.

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Language(s): eng - English
 Dates: 2022-03-142022-04-04
 Publication Status: Published online
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1038/s41598-022-08934-2
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Title: Scientific Reports
  Abbreviation : Sci. Rep.
Source Genre: Journal
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Publ. Info: London, UK : Nature Publishing Group
Pages: - Volume / Issue: 12 Sequence Number: 5618 Start / End Page: - Identifier: ISSN: 2045-2322
CoNE: https://pure.mpg.de/cone/journals/resource/2045-2322