English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
Add to Basket
 Local TagsRelease HistoryDetailsSummary
  Accelerating therapeutic protein design

ElGamacy, M. (2022). Accelerating therapeutic protein design. In Advances in Protein Chemistry and Structural Biology. New York, NY, USA: Academic Press. doi:10.1016/bs.apcsb.2022.01.004.

Item is

 

show all hide all

Basic

show hide
Item Permalink: https://hdl.handle.net/21.11116/0000-000A-6C83-9 Version Permalink: https://hdl.handle.net/21.11116/0000-000A-6C85-7
Genre: Book Chapter

Files

show Files

Locators

show

Creators

show
hide
 Creators:
ElGamacy, M1, Author           
Affiliations:
1Department Protein Evolution, Max Planck Institute for Biology Tübingen, Max Planck Society, ou_3371683              

Content

show
hide
Free keywords: -
 Abstract: Protein structures provide for defined microenvironments that can support complex pharmacological functions, otherwise unachievable by small molecules. The advent of therapeutic proteins has thus greatly broadened the range of manageable disorders. Leveraging the knowledge and recent advances in de novo protein design methods has the prospect of revolutionizing how protein drugs are discovered and developed. This review lays out the main challenges facing therapeutic proteins discovery and development, and how present and future advancements of protein design can accelerate the protein drug pipelines.

Details

show
hide
Language(s):
 Dates: 2022-032022
 Publication Status: Issued
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1016/bs.apcsb.2022.01.004
PMID: 35534117
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Advances in Protein Chemistry and Structural Biology
  Other : Adv. Protein Chem.
Source Genre: Series
 Creator(s):
Affiliations:
Publ. Info: New York, NY, USA : Academic Press
Pages: - Volume / Issue: 130 Sequence Number: - Start / End Page: - Identifier: ISSN: 1876-1623

Source 2

show
hide
Title: Protein Design and Structure
Source Genre: Book
 Creator(s):
Donev, R, Editor
Affiliations:
-
Publ. Info: -
Pages: - Volume / Issue: - Sequence Number: - Start / End Page: 85 - 118 Identifier: ISBN: 978-0-323-99229-9