Reuschl, A.-K., Mesner, D., Shivkumar, M., Whelan, M. V. X., Pallett, L. J., Guerra-Assunção, J. A., et al. (2022). HIV-1 Vpr drives a tissue residency-like phenotype during selective infection of resting memory T cells. Cell Reports, 39(2): 110650. doi:10.1016/j.celrep.2022.110650.