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  The Dynamic Reproduction Index: Accurate Determination from Incidence and Application for an Early Warning System

Conradt, R. N. J., & Herminghaus, S. (2022). The Dynamic Reproduction Index: Accurate Determination from Incidence and Application for an Early Warning System. American Journal of Epidemiology & Public Health, 6(2), 030-037. doi:10.37871/ajeph.id56.

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 Urheber:
Conradt, Robert N. J.1, Autor           
Herminghaus, Stephan1, Autor           
Affiliations:
1Group Collective phenomena far from equilibrium, Department of Dynamics of Complex Fluids, Max Planck Institute for Dynamics and Self-Organization, Max Planck Society, ou_2063306              

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 Zusammenfassung: Two methods of calculating the reproduction index from daily new infection data (incidence) are considered, one by using the generation time Gt as a shift
( RG ), and an incidence-based method directly derived from the differential equation system of an SIR epidemic dynamics model ( RI ). While the former (which
s commonly used) is shown to be at variance with the true reproduction index, we fi nd that the latter provides a sensitive detection device for intervention effects
and other events affecting the epidemic, making it well-suited for diagnostic purposes in policy making. Furthermore, we introduce a similar quantity, calc RI , which
can be calculated directly from RG . It shows largely the same behaviour as RI
, with less fi ne structure. However, it is accurate in particular in the vicinity of R = 1
, where accuracy is important for the correct prediction of epidemic dynamics. We introduce an entirely new, self-consistent method to derive, an improved corr RI
which is both accurate and contains the details of the epidemic spreading dynamics. Hence we obtain R accurately from incidence data alone. Moreover, plotting
R versus incidence reveals the orbital structure of epidemic waves, whose fi ne structure features clearly correlate with public events and interventions, thus
providing a sensitive diagnostic tool for policy making. It is demonstrated that the widespread use of only incidence as a diagnostic tool is clearly inappropriate.

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Sprache(n): eng - English
 Datum: 20222022
 Publikationsstatus: Erschienen
 Seiten: -
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: -
 Identifikatoren: DOI: 10.37871/ajeph.id56
 Art des Abschluß: -

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Titel: American Journal of Epidemiology & Public Health
Genre der Quelle: Zeitschrift
 Urheber:
Affiliations:
Ort, Verlag, Ausgabe: -
Seiten: - Band / Heft: 6 (2) Artikelnummer: - Start- / Endseite: 030 - 037 Identifikator: ISSN: 26440032