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  Cohort profile: The LIFE-adult-study

Engel, C., Wirkner, K., Zeynalova, S., Baber, R., Binder, H., Ceglarek, U., et al. (2023). Cohort profile: The LIFE-adult-study. International Journal of Epidemiology, 52(1), e66-e79. doi:10.1093/ije/dyac114.

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Basisdaten

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Datensatz-Permalink: https://hdl.handle.net/21.11116/0000-000A-951C-F Versions-Permalink: https://hdl.handle.net/21.11116/0000-000D-EF62-8
Genre: Zeitschriftenartikel

Externe Referenzen

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Urheber

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 Urheber:
Engel, Christoph1, 2, Autor
Wirkner, Kerstin1, 2, Autor
Zeynalova, Samira1, 2, Autor
Baber, Ronny2, 3, Autor
Binder, Hans4, Autor
Ceglarek, Uta2, 3, Autor
Enzenbach, Cornelia1, 2, Autor
Fuchs, Michael2, 5, Autor
Hagendorff, Andreas6, Autor
Henger, Sylvia1, 2, Autor
Hinz, Andreas7, Autor
Rauscher, Franziska G1, 2, Autor
Reusche, Matthias1, 2, Autor
Riedel-Heller, Steffi G8, Autor
Röhr, Susanne8, 9, Autor
Sacher, Julia10, 11, 12, Autor           
Sander, Christian2, 13, Autor
Schroeter, Matthias L.10, 11, Autor           
Tarnok, Attila1, 14, Autor
Treudler, Regina15, 16, Autor
Villringer, Arno10, 11, Autor           Wachter, Rolf17, AutorWitte, A. Veronica10, 11, Autor           Thiery, Joachim2, 3, AutorScholz, Markus1, 2, AutorLoeffler, Markus1, 2, AutorLIFE-Adult-Study working group, Autor               mehr..
Affiliations:
1Institute for Medical Informatics, Statistics and Epidemiology (IMISE), University of Leipzig, Germany, ou_persistent22              
2Leipzig Research Center for Civilization Diseases (LIFE), University of Leipzig, Germany, ou_persistent22              
3Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics (ILM), University of Leipzig, Germany, ou_persistent22              
4Interdisciplinary Centre for Bioinformatics (IZBI), University of Leipzig, Germany, ou_persistent22              
5Section of Phoniatrics and Audiology, Department of Otorhinolaryngology, University of Leipzig, Germany, ou_persistent22              
6Department of Cardiology, University of Leipzig, Germany, ou_persistent22              
7Department of Medical Psychology and Medical Sociology, University of Leipzig, Germany, ou_persistent22              
8Institute of Social Medicine, Occupational Health and Public Health (ISAP), University of Leipzig, Germany, ou_persistent22              
9Global Brain Health Institute (GBHI), Trinity College Dublin, Ireland, ou_persistent22              
10Clinic for Cognitive Neurology, University of Leipzig, Germany, ou_persistent22              
11Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634549              
12Minerva Research Group EGG (Emotion & neuroimaGinG) Lab, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_3230775              
13Department of Psychiatry and Psychotherapy, University Hospital Leipzig, Germany, ou_persistent22              
14Department of Preclinical Development and Validation, Fraunhofer Institute for Cell Therapy and Immunology, Leipzig, Germany, ou_persistent22              
15Department of Dermatology, Venereology and Allergology, University of Leipzig, Germany, ou_persistent22              
16Leipzig Interdisciplinary Allergy Center (LICA), University Hospital Leipzig, Germany, ou_persistent22              
17Clinic and Policlinic for Cardiology, University Hospital Leipzig, Germany, ou_persistent22              

Inhalt

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Schlagwörter: Adult; Follow-up; Germany
 Zusammenfassung: The LIFE-Adult-Study is a population-based cohort study investigating the prevalence and incidence of common diseases and subclinical disease phenotypes, the complex interactions between genetic and lifestyle factors regarding the co-occurrence and development of subclinical phenotypes and diseases, and the role of biomarkers to predict disease initiation and progression.

The study comprises an age-stratified and sex-stratified random sample of 10 000 adult individuals (aged 18–79 years) from Leipzig, Germany. The baseline assessment was conducted from August 2011 to November 2014 and the first follow-up was conducted from October 2017 to August 2021. A total of 5512 individuals completed postal follow-up questionnaires and 1799 individuals participated in a physical examination follow-up programme.

The study focuses on cardiovascular and metabolic disorders, cognition and brain function, depression, sleep disorders and electroencephalography-vigilance regulation, eye diseases, voice and allergies. The assessment programme comprises physical and medical examinations, personal interviews, self-administered questionnaires, psychometric tests, and clinical chemistry from blood and urine samples (including biobank asservation).

Details

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Sprache(n): eng - English
 Datum: 2021-09-212022-05-102022-05-282023-02
 Publikationsstatus: Erschienen
 Seiten: -
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: -
 Identifikatoren: DOI: 10.1093/ije/dyac114
PMID: 35640047
 Art des Abschluß: -

Veranstaltung

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Entscheidung

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Projektinformation

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Projektname : -
Grant ID : 031L0026
Förderprogramm : -
Förderorganisation : Federal Ministry of Education and Research (BMBF)
Projektname : -
Grant ID : R21 EY030142-01; R21 EY030631-01; R01 EY030575-01
Förderprogramm : -
Förderorganisation : National Institutes of Health (NIH)
Projektname : -
Grant ID : 209933838 A01–SFB 1052
Förderprogramm : -
Förderorganisation : Deutsche Forschungsgemeinschaft (DFG)
Projektname : LIFE—Leipzig Research Centre for Civilization Diseases, Medical Faculty of Leipzig
Grant ID : -
Förderprogramm : (713–241202; 713–241202; 14505/2470; 14575/2470)
Förderorganisation : European Union, the European Regional Development Fund (ERDF) and the Free State of Saxony

Quelle 1

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Titel: International Journal of Epidemiology
  Andere : Intern. J. Epidemiol.
Genre der Quelle: Zeitschrift
 Urheber:
Affiliations:
Ort, Verlag, Ausgabe: Oxford : Oxford University Press
Seiten: - Band / Heft: 52 (1) Artikelnummer: - Start- / Endseite: e66 - e79 Identifikator: ISSN: 0300-5771
CoNE: https://pure.mpg.de/cone/journals/resource/954925508344