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  Cohort profile: The LIFE-adult-study

Engel, C., Wirkner, K., Zeynalova, S., Baber, R., Binder, H., Ceglarek, U., Enzenbach, C., Fuchs, M., Hagendorff, A., Henger, S., Hinz, A., Rauscher, F. G., Reusche, M., Riedel-Heller, S. G., Röhr, S., Sacher, J., Sander, C., Schroeter, M. L., Tarnok, A., Treudler, R., Villringer, A., Wachter, R., Witte, A. V., Thiery, J., Scholz, M., Loeffler, M., & LIFE-Adult-Study working group (2023). Cohort profile: The LIFE-adult-study. International Journal of Epidemiology, 52(1), e66-e79. doi:10.1093/ije/dyac114.

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基本情報

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アイテムのパーマリンク: https://hdl.handle.net/21.11116/0000-000A-951C-F 版のパーマリンク: https://hdl.handle.net/21.11116/0000-000D-EF62-8
資料種別: 学術論文

ファイル

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関連URL

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作成者

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 作成者:
Engel, Christoph1, 2, 著者
Wirkner, Kerstin1, 2, 著者
Zeynalova, Samira1, 2, 著者
Baber, Ronny2, 3, 著者
Binder, Hans4, 著者
Ceglarek, Uta2, 3, 著者
Enzenbach, Cornelia1, 2, 著者
Fuchs, Michael2, 5, 著者
Hagendorff, Andreas6, 著者
Henger, Sylvia1, 2, 著者
Hinz, Andreas7, 著者
Rauscher, Franziska G1, 2, 著者
Reusche, Matthias1, 2, 著者
Riedel-Heller, Steffi G8, 著者
Röhr, Susanne8, 9, 著者
Sacher, Julia10, 11, 12, 著者           
Sander, Christian2, 13, 著者
Schroeter, Matthias L.10, 11, 著者           
Tarnok, Attila1, 14, 著者
Treudler, Regina15, 16, 著者
Villringer, Arno10, 11, 著者           Wachter, Rolf17, 著者Witte, A. Veronica10, 11, 著者           Thiery, Joachim2, 3, 著者Scholz, Markus1, 2, 著者Loeffler, Markus1, 2, 著者LIFE-Adult-Study working group, 著者               全て表示
所属:
1Institute for Medical Informatics, Statistics and Epidemiology (IMISE), University of Leipzig, Germany, ou_persistent22              
2Leipzig Research Center for Civilization Diseases (LIFE), University of Leipzig, Germany, ou_persistent22              
3Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics (ILM), University of Leipzig, Germany, ou_persistent22              
4Interdisciplinary Centre for Bioinformatics (IZBI), University of Leipzig, Germany, ou_persistent22              
5Section of Phoniatrics and Audiology, Department of Otorhinolaryngology, University of Leipzig, Germany, ou_persistent22              
6Department of Cardiology, University of Leipzig, Germany, ou_persistent22              
7Department of Medical Psychology and Medical Sociology, University of Leipzig, Germany, ou_persistent22              
8Institute of Social Medicine, Occupational Health and Public Health (ISAP), University of Leipzig, Germany, ou_persistent22              
9Global Brain Health Institute (GBHI), Trinity College Dublin, Ireland, ou_persistent22              
10Clinic for Cognitive Neurology, University of Leipzig, Germany, ou_persistent22              
11Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634549              
12Minerva Research Group EGG (Emotion & neuroimaGinG) Lab, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_3230775              
13Department of Psychiatry and Psychotherapy, University Hospital Leipzig, Germany, ou_persistent22              
14Department of Preclinical Development and Validation, Fraunhofer Institute for Cell Therapy and Immunology, Leipzig, Germany, ou_persistent22              
15Department of Dermatology, Venereology and Allergology, University of Leipzig, Germany, ou_persistent22              
16Leipzig Interdisciplinary Allergy Center (LICA), University Hospital Leipzig, Germany, ou_persistent22              
17Clinic and Policlinic for Cardiology, University Hospital Leipzig, Germany, ou_persistent22              

内容説明

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キーワード: Adult; Follow-up; Germany
 要旨: The LIFE-Adult-Study is a population-based cohort study investigating the prevalence and incidence of common diseases and subclinical disease phenotypes, the complex interactions between genetic and lifestyle factors regarding the co-occurrence and development of subclinical phenotypes and diseases, and the role of biomarkers to predict disease initiation and progression.

The study comprises an age-stratified and sex-stratified random sample of 10 000 adult individuals (aged 18–79 years) from Leipzig, Germany. The baseline assessment was conducted from August 2011 to November 2014 and the first follow-up was conducted from October 2017 to August 2021. A total of 5512 individuals completed postal follow-up questionnaires and 1799 individuals participated in a physical examination follow-up programme.

The study focuses on cardiovascular and metabolic disorders, cognition and brain function, depression, sleep disorders and electroencephalography-vigilance regulation, eye diseases, voice and allergies. The assessment programme comprises physical and medical examinations, personal interviews, self-administered questionnaires, psychometric tests, and clinical chemistry from blood and urine samples (including biobank asservation).

資料詳細

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言語: eng - English
 日付: 2021-09-212022-05-102022-05-282023-02
 出版の状態: 出版
 ページ: -
 出版情報: -
 目次: -
 査読: -
 識別子(DOI, ISBNなど): DOI: 10.1093/ije/dyac114
PMID: 35640047
 学位: -

関連イベント

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訴訟

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Project information

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Project name : -
Grant ID : 031L0026
Funding program : -
Funding organization : Federal Ministry of Education and Research (BMBF)
Project name : -
Grant ID : R21 EY030142-01; R21 EY030631-01; R01 EY030575-01
Funding program : -
Funding organization : National Institutes of Health (NIH)
Project name : -
Grant ID : 209933838 A01–SFB 1052
Funding program : -
Funding organization : Deutsche Forschungsgemeinschaft (DFG)
Project name : LIFE—Leipzig Research Centre for Civilization Diseases, Medical Faculty of Leipzig
Grant ID : -
Funding program : (713–241202; 713–241202; 14505/2470; 14575/2470)
Funding organization : European Union, the European Regional Development Fund (ERDF) and the Free State of Saxony

出版物 1

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出版物名: International Journal of Epidemiology
  その他 : Intern. J. Epidemiol.
種別: 学術雑誌
 著者・編者:
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出版社, 出版地: Oxford : Oxford University Press
ページ: - 巻号: 52 (1) 通巻号: - 開始・終了ページ: e66 - e79 識別子(ISBN, ISSN, DOIなど): ISSN: 0300-5771
CoNE: https://pure.mpg.de/cone/journals/resource/954925508344