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Abstract:
A machine-learning approach reveals antigen encoding that predicts T cell responses
An immune response involves a co-ordinated orchestra of antigen-recognizing cells (e.g., T cells) and signaling molecules to mount a specific response against a pathogen.
Although systems immunology offers a growing list of molecular interactions that are involved in antigen-specific immune responses, an understanding of how a response is mediated by different antigen characteristics is still lacking.